Technology Process of (3E)-9-benzyloxy-1-iodo-4,8-dimethylnon-3-ene
There total 6 articles about (3E)-9-benzyloxy-1-iodo-4,8-dimethylnon-3-ene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium iodide;
In
acetone;
for 15h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) LDA, 2.) hexamethylphosphoramide / 1.) THF, -78 deg C, 1 h; 2.) THF, -78 deg C to room temperature, 15 h
2: 94 percent / lithium aluminium hydride / diethyl ether / 1.5 h / 0 °C
3: 85 percent / sodium hydride / dimethylformamide / 12 h / 0 - 20 °C
4: zirconiumbis(cyclopentadienyl) dichloride, n-Bu-Li
5: triethylamine / CH2Cl2 / 1 h / -5 °C
6: 15.84 g / sodium iodide / acetone / 15 h / Ambient temperature
With
N,N,N,N,N,N-hexamethylphosphoric triamide; lithium aluminium tetrahydride; n-butyllithium; zirconocene dichloride; sodium hydride; triethylamine; sodium iodide; lithium diisopropyl amide;
In
diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 85 percent / sodium hydride / dimethylformamide / 12 h / 0 - 20 °C
2: zirconiumbis(cyclopentadienyl) dichloride, n-Bu-Li
3: triethylamine / CH2Cl2 / 1 h / -5 °C
4: 15.84 g / sodium iodide / acetone / 15 h / Ambient temperature
With
n-butyllithium; zirconocene dichloride; sodium hydride; triethylamine; sodium iodide;
In
dichloromethane; N,N-dimethyl-formamide; acetone;
