Technology Process of 4-Acetylamino-2-amino-N-(3-dimethylamino-propyl)-3-hydroxy-benzamide
There total 8 articles about 4-Acetylamino-2-amino-N-(3-dimethylamino-propyl)-3-hydroxy-benzamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium;
In
ethanol;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 73 percent / (NH4)2S / methanol / 5 h / 60 - 65 °C
2: 83 percent / methanol / 2 h / Ambient temperature
3: 66 percent / dioxane / 20 h / 8 °C
4: 89 percent / 10percent aq. NaOH / dioxane / 30 h / Ambient temperature
5: 80 percent / SOCl2 / CH2Cl2 / Heating
6: 82 percent / ethyl acetate / 24 h / Ambient temperature
7: H2 / Pd black paste / ethanol / Ambient temperature
With
diammonium sulfide; sodium hydroxide; thionyl chloride; hydrogen;
palladium;
In
1,4-dioxane; methanol; ethanol; dichloromethane; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: KOH / methanol / 6 h / Heating
2: 89 percent / 10percent aq. NaOH / dioxane / 30 h / Ambient temperature
3: 80 percent / SOCl2 / CH2Cl2 / Heating
4: 82 percent / ethyl acetate / 24 h / Ambient temperature
5: H2 / Pd black paste / ethanol / Ambient temperature
With
potassium hydroxide; sodium hydroxide; thionyl chloride; hydrogen;
palladium;
In
1,4-dioxane; methanol; ethanol; dichloromethane; ethyl acetate;
