Technology Process of 2',3',4'-Trimethoxy-3-(4-nitro-phenylazo)-biphenyl-4-ol
There total 4 articles about 2',3',4'-Trimethoxy-3-(4-nitro-phenylazo)-biphenyl-4-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 89 percent / pyridine / 1.) 0 deg C, 15 min, 2.) 5 deg C, overnight
2: 17 percent / Pd(PPh3)4, CuI / various solvent(s) / 48 h / 70 °C
3: 97 percent / 40percent aq. NaOH / 70 °C
4: 1.) NaNO2, 50percent aq. HCl, 2.) 15percent aq. NaOH / 1.) 0 deg C, 2.) r.t., 24 h
With
pyridine; hydrogenchloride; sodium hydroxide; sodium nitrite;
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0);
In
various solvent(s);
DOI:10.1021/jo00094a048
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 17 percent / Pd(PPh3)4, CuI / various solvent(s) / 48 h / 70 °C
2: 97 percent / 40percent aq. NaOH / 70 °C
3: 1.) NaNO2, 50percent aq. HCl, 2.) 15percent aq. NaOH / 1.) 0 deg C, 2.) r.t., 24 h
With
hydrogenchloride; sodium hydroxide; sodium nitrite;
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0);
In
various solvent(s);
DOI:10.1021/jo00094a048
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 97 percent / 40percent aq. NaOH / 70 °C
2: 1.) NaNO2, 50percent aq. HCl, 2.) 15percent aq. NaOH / 1.) 0 deg C, 2.) r.t., 24 h
With
hydrogenchloride; sodium hydroxide; sodium nitrite;
DOI:10.1021/jo00094a048