C₆₆H₃₀

Base Information

• Chemical Name: C₆₆H₃₀
• CAS No.: 1404452-59-0
• Molecular Formula: C₆₆H₃₀
• Molecular Weight: 822.964
• Mol file: 1404452-59-0.mol

Synonyms:

Chemical Property of C₆₆H₃₀

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₆H₃₀

There total 5 articles about C₆₆H₃₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ortho-bromobenzaldehyde (6630-33-7) → C66H30 (1404452-59-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine

2.1: triphenylphosphine / dichloromethane / 0.5 h / 0 °C

2.2: 0.5 h / 0 - 20 °C

3.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere

4.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / tetrahydrofuran / 25 h / 80 °C / Inert atmosphere

5.1: potassium carbonate / methanol / 10 h / Inert atmosphere

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; triethylamine; triphenylphosphine; lithium diisopropyl amide; In tetrahydrofuran; methanol; hexane; dichloromethane; 1.1: |Sonogashira Cross-Coupling / 4.1: |Sonogashira Cross-Coupling;

DOI:10.1002/chem.201201061

Reference yield:

2-[2-(trimethylsilyl)ethynyl]benzaldehyde (77123-58-1) → C66H30 (1404452-59-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: triphenylphosphine / dichloromethane / 0.5 h / 0 °C

1.2: 0.5 h / 0 - 20 °C

2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere

3.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / tetrahydrofuran / 25 h / 80 °C / Inert atmosphere

4.1: potassium carbonate / methanol / 10 h / Inert atmosphere

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; triethylamine; triphenylphosphine; lithium diisopropyl amide; In tetrahydrofuran; methanol; hexane; dichloromethane; 3.1: |Sonogashira Cross-Coupling;

DOI:10.1002/chem.201201061

Reference yield:

((2‐(2,2‐dibromovinyl)phenyl)ethynyl)trimethylsilane (1404452-67-0) → C66H30 (1404452-59-0)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere

2: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine / tetrahydrofuran / 25 h / 80 °C / Inert atmosphere

3: potassium carbonate / methanol / 10 h / Inert atmosphere

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; methanol; hexane; 2: |Sonogashira Cross-Coupling;

DOI:10.1002/chem.201201061

upstream raw materials:

((2‐ethynylphenyl)ethynyl)trimethylsilane

hexakis({2-[(trimethylsilyl)ethynyl]phenyl}ethynyl)benzene

ortho-bromobenzaldehyde

2-[2-(trimethylsilyl)ethynyl]benzaldehyde