Benzene, 1-bromo-3-methoxy-2,5-bis(methoxymethoxy)-

Base Information

Chemical Name:Benzene, 1-bromo-3-methoxy-2,5-bis(methoxymethoxy)-
CAS No.:133099-84-0
Molecular Formula:C11H15BrO5
Molecular Weight:307.141
Hs Code.:
DSSTox Substance ID:DTXSID90454437
Wikidata:Q82275959

Synonyms:133099-84-0;Benzene, 1-bromo-3-methoxy-2,5-bis(methoxymethoxy)-;DTXSID90454437

Suppliers and Price of Benzene, 1-bromo-3-methoxy-2,5-bis(methoxymethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzene, 1-bromo-3-methoxy-2,5-bis(methoxymethoxy)-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:306.01029
Heavy Atom Count:17
Complexity:204

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCOC1=CC(=C(C(=C1)Br)OCOC)OC

Technology Process of Benzene, 1-bromo-3-methoxy-2,5-bis(methoxymethoxy)-

There total 5 articles about Benzene, 1-bromo-3-methoxy-2,5-bis(methoxymethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 61654-67-9
2,5-dihydroxy-3-methoxy-1-bromobenzene

: 107-30-2
chloromethyl methyl ether

: 133099-84-0
5-bromo-3-methoxy-1,4-bis(methoxymethoxy)benzene

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;
DOI:10.1016/j.ejmech.2020.112620

Reference yield:

: 2973-76-4
5-bromo-4-hydroxy-3-methoxybenzaldehyde

: 133099-84-0
5-bromo-3-methoxy-1,4-bis(methoxymethoxy)benzene

Guidance literature:: Multi-step reaction with 4 steps

1: 1) Bu₄NI, NaH / 1) DMF, 10 min., r.t., 2) r.t., 24 h

2: m-chloroperbenzoic acid / CH₂Cl₂ / 16 h / Ambient temperature

3: 10percent aq.KOH / methanol / 12 h / 25 °C

4: 1) Bu₄NI, NaH / 1) DMF, r.t., 0.5 h, 2) 72 h, 25 deg C

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane;
DOI:10.1021/jo00006a029

Reference yield:

: 2363-14-6
5-Bromo-3-methoxy-4-(methoxymethoxy)benzene-1-carboxaldehyde

: 133099-84-0
5-bromo-3-methoxy-1,4-bis(methoxymethoxy)benzene

Guidance literature:: Multi-step reaction with 3 steps

1: m-chloroperbenzoic acid / CH₂Cl₂ / 16 h / Ambient temperature

2: 10percent aq.KOH / methanol / 12 h / 25 °C

3: 1) Bu₄NI, NaH / 1) DMF, r.t., 0.5 h, 2) 72 h, 25 deg C

With potassium hydroxide; tetra-(n-butyl)ammonium iodide; sodium hydride; 3-chloro-benzenecarboperoxoic acid; In methanol; dichloromethane;
DOI:10.1021/jo00006a029