1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

Base Information

Chemical Name:1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium
CAS No.:1429438-85-6
Molecular Formula:C₆₅H₇₄N₇O₁₆S₂
Molecular Weight:1273.47
Hs Code.:

1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

Synonyms:

Suppliers and Price of 1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

There total 13 articles about 1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: (S)-4-tert-butyl 1-(4-methoxybenzyl) 2-(((Z)-(1-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)-2-(((6R,7R)-3-(iodomethyl)-2-(((4-methoxybenzyl)oxy)carbonyl)-5-oxido-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)amino)-2-oxoethylidene)amino)oxy)succinate

: 1429438-84-5
3-((4-methoxybenzyl)oxy)-1-methyl-6-(pyrrolidin-1-ylmethyl)quinolin-4(1H)-one

: 1429438-85-6
1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

Guidance literature:: (S)-4-tert-butyl 1-(4-methoxybenzyl) 2-(((Z)-(1-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)-2-(((6R,7R)-3-(iodomethyl)-2-(((4-methoxybenzyl)oxy)carbonyl)-5-oxido-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)amino)-2-oxoethylidene)amino)oxy)succinate; 3-((4-methoxybenzyl)oxy)-1-methyl-6-(pyrrolidin-1-ylmethyl)quinolin-4(1H)-one; In N,N-dimethyl acetamide; at 40 ℃; for 3h; Inert atmosphere;

With phosphorus tribromide; In N,N-dimethyl acetamide; N,N-dimethyl-formamide; at -40 ℃; for 0.666667h; Inert atmosphere;

Reference yield:

: 1338730-20-3
(S)-4-tert-butyl 1-(4-methoxybenzyl) 2-(((Z)-(1-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)-2-(((6R,7R)-3-(chloromethyl)-2-(((4-methoxybenzyl)oxy)carbonyl)-5-oxido-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)amino)-2-oxoethylidene)amino)oxy)succinate

: 1429438-85-6
1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium iodide / acetone / 2 h / 20 °C / Inert atmosphere

2.1: N,N-dimethyl acetamide / 3 h / 40 °C / Inert atmosphere

2.2: 0.67 h / -40 °C / Inert atmosphere

With sodium iodide; In N,N-dimethyl acetamide; acetone;

Reference yield:

: 1429438-79-8
ethyl 3-acetyl-1-methyl-4-oxo-1,4-dihydroquinolin-6-carboxylate

: 1429438-85-6
1-(((6R,7R)-7-((Z)-2-((((S)-4-(tert-butoxy)-1-((4-methoxybenzyl)oxy)-1,4-dioxobutan-2-yl)oxy)imino)-2-(2-((tert-butoxycarbonyl)amino)thiazol-4-yl)acetamido)-2-(((4-methoxybenzyl)oxy)carbonyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-1-((3-((4-methoxybenzyl)oxy)-1-methyl-4-oxo-1,4-dihydroquinolin-6-yl)methyl)pyrrolidin-1-ium

Guidance literature:: Multi-step reaction with 8 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.1: methanol / 65 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 0 °C / Inert atmosphere

3.2: 2 h / 75 °C / Inert atmosphere

3.3: 20 °C / Inert atmosphere

4.1: triethylamine / tetrahydrofuran / 1.5 h / 20 °C / Inert atmosphere

5.1: sodium tetrahydroborate / ethanol / 1.5 h / Inert atmosphere

6.1: Dess-Martin periodane / dichloromethane / 1 h / 20 °C / Inert atmosphere

7.1: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 1.5 h / Inert atmosphere

8.1: N,N-dimethyl acetamide / 3 h / 40 °C / Inert atmosphere

8.2: 0.67 h / -40 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; sodium tris(acetoxy)borohydride; sodium hydride; Dess-Martin periodane; acetic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl acetamide; 1,2-dichloro-ethane; N,N-dimethyl-formamide;