Technology Process of C18H21N5O5
There total 9 articles about C18H21N5O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: hydroxylamine; sodium hydroxide / Inert atmosphere
2: 1,1'-carbonyldiimidazole / Inert atmosphere
3: toluene / 130 °C / Inert atmosphere
4: sodium hydroxide / Inert atmosphere
5: 1-hydroxy-pyrrolidine-2,5-dione; ammonium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / Inert atmosphere
6: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / Inert atmosphere
7: triethylsilane; trifluoroacetic acid / Inert atmosphere
8: lithium hydroxide / Inert atmosphere
With
triethylsilane; ammonium hydroxide; tris-(dibenzylideneacetone)dipalladium(0); 1-hydroxy-pyrrolidine-2,5-dione; hydroxylamine; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1,1'-carbonyldiimidazole; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; trifluoroacetic acid; sodium hydroxide; lithium hydroxide;
In
1,4-dioxane; toluene;
DOI:10.1016/j.bmcl.2010.11.116
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1,1'-carbonyldiimidazole / Inert atmosphere
2: toluene / 130 °C / Inert atmosphere
3: sodium hydroxide / Inert atmosphere
4: 1-hydroxy-pyrrolidine-2,5-dione; ammonium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / Inert atmosphere
5: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / Inert atmosphere
6: triethylsilane; trifluoroacetic acid / Inert atmosphere
7: lithium hydroxide / Inert atmosphere
With
triethylsilane; ammonium hydroxide; tris-(dibenzylideneacetone)dipalladium(0); 1-hydroxy-pyrrolidine-2,5-dione; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1,1'-carbonyldiimidazole; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; trifluoroacetic acid; sodium hydroxide; lithium hydroxide;
In
1,4-dioxane; toluene;
DOI:10.1016/j.bmcl.2010.11.116
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydroxide / Inert atmosphere
2: 1-hydroxy-pyrrolidine-2,5-dione; ammonium hydroxide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / Inert atmosphere
3: tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene / 1,4-dioxane / Inert atmosphere
4: triethylsilane; trifluoroacetic acid / Inert atmosphere
5: lithium hydroxide / Inert atmosphere
With
triethylsilane; ammonium hydroxide; tris-(dibenzylideneacetone)dipalladium(0); 1-hydroxy-pyrrolidine-2,5-dione; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; trifluoroacetic acid; sodium hydroxide; lithium hydroxide;
In
1,4-dioxane;
DOI:10.1016/j.bmcl.2010.11.116