Technology Process of 8-exo-Hydroxy-2-noradamantanone
There total 6 articles about 8-exo-Hydroxy-2-noradamantanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
methanol; water;
for 3h;
Ambient temperature;
DOI:10.1021/jo00181a007
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 91.4 percent / MCPBA, aq. NaHCO3 / CH2Cl2 / 2 h / Ambient temperature
2: 92.8 percent / BF3*Et2O / 0.5 h / Ambient temperature
3: 78.4 percent / CrO3, H3O+ / acetone / 0.17 h / Ambient temperature
4: 94.7 percent / KOH / methanol; H2O / 3 h / Ambient temperature
With
chromium(VI) oxide; potassium hydroxide; boron trifluoride diethyl etherate; oxonium; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
methanol; dichloromethane; water; acetone;
DOI:10.1021/jo00181a007
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 91.6 percent / LiAlH4 / diethyl ether / 4 h / Heating
2: 72 percent / HMPT / 5 h / 210 - 215 °C
3: 91.4 percent / MCPBA, aq. NaHCO3 / CH2Cl2 / 2 h / Ambient temperature
4: 92.8 percent / BF3*Et2O / 0.5 h / Ambient temperature
5: 78.4 percent / CrO3, H3O+ / acetone / 0.17 h / Ambient temperature
6: 94.7 percent / KOH / methanol; H2O / 3 h / Ambient temperature
With
chromium(VI) oxide; N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydroxide; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; oxonium; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
methanol; diethyl ether; dichloromethane; water; acetone;
DOI:10.1021/jo00181a007
