Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester

Base Information

• Chemical Name: Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester
• CAS No.: 438189-35-6
• Molecular Formula: C₄₃H₄₆NO₉P
• Molecular Weight: 751.813
• Mol file: 438189-35-6.mol

Synonyms:

Chemical Property of Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester

There total 5 articles about Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2,4,6-tri-O-benzyl-1-thio-β-D-galactopyranoside (152964-77-7) → Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester (438189-35-6)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridine

2: NaN₃

3: SnCl₂; PhSH; Et₃N

4: pyridine

With pyridine; sodium azide; thiophenol; triethylamine; tin(ll) chloride;

DOI:10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K

Reference yield:

(2S,3R,4S,5R,6S)-4,5-Bis-benzyloxy-2-benzyloxymethyl-6-ethylsulfanyl-tetrahydro-pyran-3-ylamine → Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester (438189-35-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

With pyridine;

DOI:10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K

Reference yield:

(2S,3R,4S,5R,6S)-3-Azido-4,5-bis-benzyloxy-2-benzyloxymethyl-6-ethylsulfanyl-tetrahydro-pyran (345197-25-3) → Phosphoric acid (2R,3R,4S,5R,6S)-5-acetylamino-3,4-bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl ester dibenzyl ester (438189-35-6)

Guidance literature:

Multi-step reaction with 3 steps

1: SnCl₂; PhSH; Et₃N

2: pyridine

With pyridine; thiophenol; triethylamine; tin(ll) chloride;

DOI:10.1002/1521-3773(20010417)40:8<1502::AID-ANIE1502>3.0.CO;2-K

upstream raw materials:

phosphoric acid dibenzyl ester

Ethyl 4-acetamido-2,3,6-tri-O-benzyl-4-deoxy-1-thio-β-D-glucopyranoside

ethyl 2,4,6-tri-O-benzyl-1-thio-β-D-galactopyranoside

(2S,3R,4S,5R,6S)-3-Azido-4,5-bis-benzyloxy-2-benzyloxymethyl-6-ethylsulfanyl-tetrahydro-pyran