DTBA

Base Information

• Chemical Name: DTBA
• CAS No.: 1363376-98-0
• Molecular Formula: C₄H₁₁NS₂*ClH
• Molecular Weight: 173.731
• Mol file: 1363376-98-0.mol

Synonyms:

Chemical Property of DTBA

Chemical Property:

• Melting Point: 210-225°C
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

DithiobutylamineHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

Useful:

• Uses: Dithiobutylamine or DTBA is a new biological reducing reagent with enhanced properties over other commonly used reagents. DTBA was shown to reduce small molecule disulfides 3-5x faster than DTT and was able to reduce (activate) the cysteine dependent protease papain 14x faster than DTT. In addition, due to the presence of the primary amine group, removal of DTBA from mixtures after use is simplified and can be achieved using cation exchange resin.

Technology Process of DTBA

There total 1 articles about DTBA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

[(S)-S, S'-2-(tert-butoxycarbonylamino)butane-1,4-diyl diethanethioate] → (S)-2-aminobutane-1,4-dithiol hydrochloride (1363376-98-0)

Guidance literature:

[(S)-S, S'-2-(tert-butoxycarbonylamino)butane-1,4-diyl diethanethioate]; With hydrogenchloride; In methanol; for 4h; Inert atmosphere; Reflux;

With phosphorus pentoxide; potassium hydroxide; for 48h;

DOI:10.1021/ja211931f

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