Methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate

Base Information

Chemical Name:Methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate
CAS No.:1260650-61-0
Molecular Formula:C₁₃H₁₆ClNO₄
Molecular Weight:285.727
Hs Code.:
DSSTox Substance ID:DTXSID801140542

Synonyms:1260650-61-0;Methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate;SCHEMBL13471215;DTXSID801140542;MFCD11976870;D84528;Methyl4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate;METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-3-CHLOROBENZOATE;METHYL 4-{[(TERT-BUTOXY)CARBONYL]AMINO-3-CHLOROBENZOATE;Benzoic acid, 3-chloro-4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester

Suppliers and Price of Methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
methyl4-(tert-butoxycarbonylamino)-3-chlorobenzoate 95
5g
$ 1467.00

Crysdot
Methyl4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate 97%
1g
$ 635.00

American Custom Chemicals Corporation
METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-3-CHLOROBENZOATE 95.00%
5MG
$ 501.77

Alichem
Methyl4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate
1g
$ 506.66

Total 0 raw suppliers

Chemical Property of Methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:285.0767857
Heavy Atom Count:19
Complexity:340

Purity/Quality:: methyl4-(tert-butoxycarbonylamino)-3-chlorobenzoate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=C(C=C(C=C1)C(=O)OC)Cl

Technology Process of Methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate

There total 4 articles about Methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 164596-20-7
4-tert-butoxycarbonylamino-benzoic acid methyl ester

: 1260650-61-0
methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate

Guidance literature:: With 1,3-dichloro-5,5-dimethylhydantoin; diisopropylamine hydrochloride; In toluene; at 25 ℃; for 14h; regioselective reaction; Darkness; Green chemistry;
DOI:10.1002/anie.201607388

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 84228-44-4
methyl 4-amino-3-chlorobenzoate

: 1260650-61-0
methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate

Guidance literature:: di-tert-butyl dicarbonate; methyl 4-amino-3-chlorobenzoate; With dmap; In tetrahydrofuran;

With potassium carbonate; In methanol; for 2h; Reflux;

Reference yield:

: 2486-71-7
4-amino-3-chlorobenzoic acid

: 1260650-61-0
methyl 4-((tert-butoxycarbonyl)amino)-3-chlorobenzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid / Dean-Stark

2.1: dmap / tetrahydrofuran

2.2: 2 h / Reflux

With dmap; sulfuric acid; In tetrahydrofuran;