Technology Process of alternaramide
There total 18 articles about alternaramide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: methanol; water; lithium hydroxide / tetrahydrofuran
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane
3: hydrogenchloride / 1,4-dioxane
4: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane
5: tetrabutyl ammonium fluoride / tetrahydrofuran
6: methanol; water; lithium hydroxide / tetrahydrofuran
7: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane
With
hydrogenchloride; methanol; tetrabutyl ammonium fluoride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; lithium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1055/s-0030-1259915
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane
2: methanol; water; lithium hydroxide / tetrahydrofuran
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane
4: hydrogenchloride / 1,4-dioxane
5: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane
6: tetrabutyl ammonium fluoride / tetrahydrofuran
7: methanol; water; lithium hydroxide / tetrahydrofuran
8: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane
With
hydrogenchloride; methanol; tetrabutyl ammonium fluoride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; lithium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1055/s-0030-1259915
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sulfuric acid; sodium nitrite
2: 1H-imidazole / N,N-dimethyl-formamide
3: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane
4: tetrabutyl ammonium fluoride / tetrahydrofuran
5: methanol; water; lithium hydroxide / tetrahydrofuran
6: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane
With
1H-imidazole; methanol; sulfuric acid; tetrabutyl ammonium fluoride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; N-ethyl-N,N-diisopropylamine; lithium hydroxide; sodium nitrite;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-0030-1259915