Technology Process of C28H33N7O*ClH
There total 4 articles about C28H33N7O*ClH which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
1,4-dioxane;
at 0 - 20 ℃;
DOI:10.1021/jm301190s
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0 - 20 °C
2: hydrogenchloride / 1,4-dioxane / 0 - 20 °C
With
hydrogenchloride; N-ethyl-N,N-diisopropylamine; HATU;
In
1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm301190s
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 16 h / 20 °C
2: potassium carbonate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride / 1,4-dioxane / 120 °C
3: sodium hydroxide; water / methanol
4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0 - 20 °C
5: hydrogenchloride / 1,4-dioxane / 0 - 20 °C
With
hydrogenchloride; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; di-isopropyl azodicarboxylate; water; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; HATU; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; methanol; N,N-dimethyl-formamide;
1: |Mitsunobu Displacement / 2: |Suzuki Coupling;
DOI:10.1021/jm301190s