N-Biotinyl Dopamine

Base Information

• Chemical Name: N-Biotinyl Dopamine
• CAS No.: 241142-94-9
• Molecular Formula: C₁₈H₂₅N₃O₄S
• Molecular Weight: 379.48
• Mol file: 241142-94-9.mol

Synonyms:

Chemical Property of N-Biotinyl Dopamine

Chemical Property:

• Melting Point: 174-176°C
• Boiling Point: 782.6±60.0 °C(Predicted)
• PKA: 9.79±0.10(Predicted)
• Density: 1.288±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly, Sonicated)

Purity/Quality:

99.90% ^*data from raw suppliers

N-Biotinyl Dopamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: N-Biotinyl dopamine was used as a bifunctional compound to mediate the oxidation of β-nicotinamide adenine dinucleotide (NADH).

Technology Process of N-Biotinyl Dopamine

There total 3 articles about N-Biotinyl Dopamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

N-biotinyl-2-(3,4-dibenzyloxyphenyl)ethylamine (1357289-91-8) → N-biotinyl-2-(3,4-dihydroxyphenyl)ethylamine (241142-94-9)

Guidance literature:

With 20 % Pd(OH)2/C; hydrogen; In methanol; dichloromethane; at 30 ℃; for 2h; under 52505.3 Torr; Autoclave;

DOI:10.1002/anie.201103469

Reference yield: 40.0%

sulfosuccinimidobiotin (194041-65-1) + dopamine hydrochloride (62-31-7) → N-biotinyl-2-(3,4-dihydroxyphenyl)ethylamine (241142-94-9)

Guidance literature:

With potassium dihydrogenphosphate; In water; at 4 ℃; for 26h; pH=7.0;

DOI:10.1016/j.bmc.2009.03.031

Reference yield:

dopamine hydrochloride (62-31-7) + biotin (58-85-5,22879-79-4) → N-biotinyl-2-(3,4-dihydroxyphenyl)ethylamine (241142-94-9)

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; N,N-dimethyl-formamide; for 30h;

DOI:10.1021/ja045220h

upstream raw materials:

dopamine hydrochloride

biotin

sulfosuccinimidobiotin

N-biotinyl-2-(3,4-dibenzyloxyphenyl)ethylamine

Refernces

• 1、 De Cogan, Felicity,Booth, Andrew,Gough, Julie E.,Webb, Simon J.. "Conversion of magnetic impulses into cellular responses by self-assembled nanoparticle-vesicle hydrogels". supporting information; experimental part. p. 12290 - 12293. Retrieved 2012/01/30.