C₂₅H₃₅N₅O₈

Base Information

• Chemical Name: C₂₅H₃₅N₅O₈
• CAS No.: 1469300-37-5
• Molecular Formula: C₂₅H₃₅N₅O₈
• Molecular Weight: 533.582
• Mol file: 1469300-37-5.mol

Synonyms:

Chemical Property of C₂₅H₃₅N₅O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₅N₅O₈

There total 8 articles about C₂₅H₃₅N₅O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H25NO6 (1469300-36-4) + C7H12N4O3 (1469300-35-3) → C25H35N5O8 (1469300-37-5)

Guidance literature:

C₁₈H₂₅NO₆; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

C₇H₁₂N₄O₃; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201304239

Reference yield:

C13H14N4O2 (1469300-41-1) → C25H35N5O8 (1469300-37-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: acetyl chloride / 4.5 h / 0 - 50 °C / Inert atmosphere

2.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 6 h / 760.05 Torr

3.1: lithium hydroxide monohydrate; water / d⁽⁴⁾-methanol; tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

4.2: 12 h / 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; palladium 10% on activated carbon; water; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; acetyl chloride; In tetrahydrofuran; dichloromethane; d⁽⁴⁾-methanol; ethyl acetate;

DOI:10.1002/anie.201304239

Reference yield:

C13H17N3O3 → C25H35N5O8 (1469300-37-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: boron trifluoride diethyl etherate / acetonitrile / 0.17 h / 0 °C / Inert atmosphere

2.1: acetyl chloride / 4.5 h / 0 - 50 °C / Inert atmosphere

3.1: palladium 10% on activated carbon; hydrogen / ethyl acetate / 6 h / 760.05 Torr

4.1: lithium hydroxide monohydrate; water / d⁽⁴⁾-methanol; tetrahydrofuran / 1 h / 0 - 20 °C / Inert atmosphere

5.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

5.2: 12 h / 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; palladium 10% on activated carbon; boron trifluoride diethyl etherate; water; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; acetyl chloride; In tetrahydrofuran; dichloromethane; d⁽⁴⁾-methanol; ethyl acetate; acetonitrile;

DOI:10.1002/anie.201304239

upstream raw materials:

C₁₄H₁₇N₃O₄

C₁₂H₂₁NO₆

C₁₂H₂₀N₄O₅

C₁₉H₂₇NO₆

Downstream raw materials:

C₄₄H₅₈N₁₀O₁₃

C₂₀H₂₇N₅O₆

C₂₄H₃₃N₅O₈