2-isopropyl-3,5-diphenylfuran

Base Information

• Chemical Name: 2-isopropyl-3,5-diphenylfuran
• CAS No.: 1274764-47-4
• Molecular Formula: C₁₉H₁₈O
• Molecular Weight: 262.351
• Mol file: 1274764-47-4.mol

Synonyms:

Chemical Property of 2-isopropyl-3,5-diphenylfuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-isopropyl-3,5-diphenylfuran

There total 2 articles about 2-isopropyl-3,5-diphenylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R)-3-isopropyl-2-phenyl-2-(phenylethynyl)oxirane → 2-isopropyl-3,5-diphenylfuran (1274764-47-4)

Guidance literature:

With indium(III) chloride; In toluene; at 70 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1021/jo2001353

Reference yield:

2-bromo-3-methyl-1-phenylbutan-1-one (147749-67-5,50735-03-0) + phenylacetylene (536-74-3) → 2-isopropyl-3,5-diphenylfuran (1274764-47-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

2.1: indium(III) chloride / toluene / 0.33 h / 70 °C / Inert atmosphere

With indium(III) chloride; n-butyllithium; In tetrahydrofuran; toluene;

DOI:10.1021/jo2001353

upstream raw materials:

2-bromo-3-methyl-1-phenylbutan-1-one

phenylacetylene