Ethyl 4,5,10-trioxo-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 4,5,10-trioxo-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate
CAS No.:13388-74-4
Molecular Formula:C16H11NO5
Molecular Weight:297.267
Hs Code.:
NSC Number:125388
DSSTox Substance ID:DTXSID90298691
Nikkaji Number:J1.999.734K
Wikidata:Q82040671
Mol file:13388-74-4.mol

Synonyms:13388-74-4;ethyl 4,5,10-trioxo-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate;NSC125388;DTXSID90298691;VKUQGWQKHHCKDV-UHFFFAOYSA-N;NSC-125388;3-Carboethoxy-4-hydroxybenzo[g]quinoline-5,10-dione;Ethyl 4-hydroxy-5,10-dioxo-5,10-dihydrobenzo[g]quinoline-3-carboxylate #

Suppliers and Price of Ethyl 4,5,10-trioxo-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethyl 4,5,10-trioxo-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

Chemical Property:

Vapor Pressure:2.1E-09mmHg at 25°C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:297.06372245
Heavy Atom Count:22
Complexity:643

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CNC2=C(C1=O)C(=O)C3=CC=CC=C3C2=O

Technology Process of Ethyl 4,5,10-trioxo-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate

There total 2 articles about Ethyl 4,5,10-trioxo-1,4,5,10-tetrahydrobenzo[g]quinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 40516-46-9
diethyl (ethoxymethylene)malonate

: 2348-81-4
2-amino-1,4-naphthoquinone

: 13388-74-4
ethyl 1H-benzo[g]quinoline-4,5,10-trione-3-carboxylate

Guidance literature:: In diphenylether; at 210 ℃; for 15h;

Reference yield:

: 2348-81-4
2-amino-1,4-naphthoquinone

: 13388-74-4
ethyl 1H-benzo[g]quinoline-4,5,10-trione-3-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 42 percent / hydroxylamine hydrochloride, NaOH / acetonitrile; H₂O / 7 h / 90 °C

2: trifluoroacetic acid / Heating

3: 60 percent / various solvent(s) / 7 h / Heating

With sodium hydroxide; hydroxylamine hydrochloride; In water; acetonitrile; trifluoroacetic acid;
DOI:10.1016/S0040-4020(01)81213-8

Reference yield: 18.0%

: 13388-74-4
ethyl 1H-benzo[g]quinoline-4,5,10-trione-3-carboxylate

: 100-44-7
benzyl chloride

: 77-78-1
dimethyl sulfate

: 680859-85-2
ethyl 10-benzyloxy-5-hydroxybenzo[g]quinolin-4(1H)-one-3-carboxylate

Guidance literature:: ethyl 1H-benzo[g]quinoline-4,5,10-trione-3-carboxylate; benzyl chloride; With sodium dithionite; tetrabutylammomium bromide; In tetrahydrofuran; water; at 20 ℃; for 0.25h;

dimethyl sulfate; With potassium hydroxide; In tetrahydrofuran; water; at 90 ℃; for 2h;