C₄₄H₆₃N₅O₁₃S₃

Base Information

• Chemical Name: C₄₄H₆₃N₅O₁₃S₃
• CAS No.: 1373514-07-8
• Molecular Formula: C₄₄H₆₃N₅O₁₃S₃
• Molecular Weight: 966.208
• Mol file: 1373514-07-8.mol

Synonyms:

Chemical Property of C₄₄H₆₃N₅O₁₃S₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₆₃N₅O₁₃S₃

There total 13 articles about C₄₄H₆₃N₅O₁₃S₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ZC3M-AE-NHS (1307864-00-1) + BrH*C10H25N3O3S → C44H63N5O13S3 (1373514-07-8)

Guidance literature:

With sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

DOI:10.1039/c2ob00022a

Reference yield:

2-methoxyacridine-9-carboxylic acid (130266-57-8) → C44H63N5O13S3 (1373514-07-8)

Guidance literature:

Multi-step reaction with 7 steps

1.1: pyridine; p-toluenesulfonyl chloride / 4 h / 20 °C / Inert atmosphere

2.1: boron tribromide / dichloromethane / 4 h / 20 °C

2.2: 16 h / 0 - 20 °C

3.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

4.1: 2,6-di-tert-butyl-pyridine / 24 h / 150 °C / Inert atmosphere; Ionic liquid

5.1: hydrogenchloride / water / 2 h / Reflux; Inert atmosphere

6.1: N-ethyl-N,N-diisopropylamine / water; N,N-dimethyl-formamide / 0.25 h / 20 °C

7.1: sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 0.5 h / 20 °C

With pyridine; hydrogenchloride; 2,6-di-tert-butyl-pyridine; di-isopropyl azodicarboxylate; boron tribromide; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; p-toluenesulfonyl chloride; triphenylphosphine; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; 3.1: Mitsunobu reaction;

DOI:10.1039/c2ob00022a

Reference yield:

1-bromo-4-methoxy-benzene (104-92-7) → C44H63N5O13S3 (1373514-07-8)

Guidance literature:

Multi-step reaction with 9 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / Inert atmosphere

1.2: 145 °C / Inert atmosphere

2.1: potassium hydroxide / water / 4 h / Inert atmosphere; Reflux

3.1: pyridine; p-toluenesulfonyl chloride / 4 h / 20 °C / Inert atmosphere

4.1: boron tribromide / dichloromethane / 4 h / 20 °C

4.2: 16 h / 0 - 20 °C

5.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

6.1: 2,6-di-tert-butyl-pyridine / 24 h / 150 °C / Inert atmosphere; Ionic liquid

7.1: hydrogenchloride / water / 2 h / Reflux; Inert atmosphere

8.1: N-ethyl-N,N-diisopropylamine / water; N,N-dimethyl-formamide / 0.25 h / 20 °C

9.1: sodium hydrogencarbonate / water; N,N-dimethyl-formamide / 0.5 h / 20 °C

With pyridine; hydrogenchloride; 2,6-di-tert-butyl-pyridine; di-isopropyl azodicarboxylate; boron tribromide; sodium hydride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; p-toluenesulfonyl chloride; triphenylphosphine; potassium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; mineral oil; 5.1: Mitsunobu reaction;

DOI:10.1039/c2ob00022a

upstream raw materials:

1-bromo-4-methoxy-benzene

2-methoxyacridine-9-carboxylic acid

C₉H₉ClO₂

C₃₅H₄₂N₂O₁₁S₂

Downstream raw materials:

C₅₃H₇₂N₆O₁₈S₃