Technology Process of Fmoc-Phe-D-Ala-Thr-NHBn
There total 4 articles about Fmoc-Phe-D-Ala-Thr-NHBn which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trifluoroacetic acid / methanol; chloroform / 2.17 h / 0 °C
1.2: pH 8 / Saturated solution
2.1: copper(II) acetate monohydrate; benzotriazol-1-ol / N,N-dimethyl-formamide / 3.17 h
3.1: water; trifluoroacetic acid / 3 h
With
water; copper(II) acetate monohydrate; benzotriazol-1-ol; trifluoroacetic acid;
In
methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/ja207133t
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydrogen sulfide monohydrate / methanol / 2.5 h / 20 °C
2: copper(II) acetate monohydrate; benzotriazol-1-ol / N,N-dimethyl-formamide / 3.17 h
3: water; trifluoroacetic acid / 3 h
With
sodium hydrogen sulfide monohydrate; water; copper(II) acetate monohydrate; benzotriazol-1-ol; trifluoroacetic acid;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1021/ja207133t
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(II) acetate monohydrate; benzotriazol-1-ol / N,N-dimethyl-formamide / 3.17 h
2: water; trifluoroacetic acid / 3 h
With
water; copper(II) acetate monohydrate; benzotriazol-1-ol; trifluoroacetic acid;
In
N,N-dimethyl-formamide;
DOI:10.1021/ja207133t
