Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide

Base Information

• Chemical Name: Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide
• CAS No.: 80967-82-4
• Molecular Formula: C₂₅H₂₆N₂O₃
• Molecular Weight: 402.493
• Mol file: 80967-82-4.mol

Synonyms:

Chemical Property of Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide

There total 4 articles about Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N'-ethylbenzilohydrazide (80960-29-8) + Hydroxy-di-m-tolyl-acetic acid N'-ethyl-hydrazide (80960-31-2) → Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide (80967-82-4)

Guidance literature:

In benzene;

Reference yield:

ethylidenehydrazide of benzilic acid (73162-17-1) → Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide (80967-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 45 percent / LiAlH₄ / diethyl ether / 4 h / Heating

2: 96 percent / benzene

With lithium aluminium tetrahydride; In diethyl ether; benzene;

Reference yield:

Hydroxy-di-m-tolyl-acetic acid eth-(E)-ylidene-hydrazide (80960-45-8) → Benzoic acid N-ethyl-N'-(2-hydroxy-2,2-di-m-tolyl-acetyl)-hydrazide (80967-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 43 percent / LiAlH₄ / diethyl ether / 4 h / Heating

2: 96 percent / benzene

With lithium aluminium tetrahydride; In diethyl ether; benzene;

upstream raw materials:

N'-ethylbenzilohydrazide

Hydroxy-di-m-tolyl-acetic acid N'-ethyl-hydrazide

benzoyl chloride

ethylidenehydrazide of benzilic acid

Refernces