Technology Process of C30H25FN2O4
There total 4 articles about C30H25FN2O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium tert-butylate; palladium diacetate; XPhos;
In
toluene; tert-butyl alcohol;
at 90 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/jm301539x
- Guidance literature:
-
Multi-step reaction with 4 steps
1: oxalyl dichloride; N,N-dimethyl-formamide / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere
2: triethylamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
3: palladium 10% on activated carbon; hydrogen / ethyl acetate
4: palladium diacetate; XPhos; potassium tert-butylate / toluene; tert-butyl alcohol / 3 h / 90 °C / Inert atmosphere
With
oxalyl dichloride; palladium 10% on activated carbon; potassium tert-butylate; hydrogen; palladium diacetate; triethylamine; N,N-dimethyl-formamide; XPhos;
In
tetrahydrofuran; ethyl acetate; toluene; tert-butyl alcohol;
4: |Buchwald-Hartwig Coupling;
DOI:10.1021/jm301539x
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / ethyl acetate
2: palladium diacetate; XPhos; potassium tert-butylate / toluene; tert-butyl alcohol / 3 h / 90 °C / Inert atmosphere
With
palladium 10% on activated carbon; potassium tert-butylate; hydrogen; palladium diacetate; XPhos;
In
ethyl acetate; toluene; tert-butyl alcohol;
2: |Buchwald-Hartwig Coupling;
DOI:10.1021/jm301539x
