C₃₈H₅₁N₅O₆S

Base Information

Chemical Name:C₃₈H₅₁N₅O₆S
CAS No.:1427513-72-1
Molecular Formula:C₃₈H₅₁N₅O₆S
Molecular Weight:705.919
Hs Code.:

C<sub>38</sub>H<sub>51</sub>N<sub>5</sub>O<sub>6</sub>S

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₃₈H₅₁N₅O₆S

Chemical Property:

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Technology Process of C₃₈H₅₁N₅O₆S

There total 16 articles about C₃₈H₅₁N₅O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1427513-67-4
(2S,4R)-methyl 4-(2-((1R,3R)-1-hydroxy-3-((2S,3S)-3-methyl-2-((R)-1-methylpiperidine-2-carboxamido)pentanamido)-3-phenylpropyl)thiazole-4-carboxamido)-2-methyl-5-phenylpentanoate

: 1427513-72-1
C₃₈H₅₁N₅O₆S

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 72h; Inert atmosphere;
DOI:10.1039/c3ob27111k

Reference yield:

: 1427513-35-6
ethyl 2-((1R,3R)-3-(tert-butoxycarbonylamino)-1-hydroxy-3-phenylpropyl)thiazole-4-carboxylate

: 1427513-72-1
C₃₈H₅₁N₅O₆S

Guidance literature:: Multi-step reaction with 9 steps

1: dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 0 - 20 °C

3: hydrogenchloride; sodium hydrogencarbonate / water

4: lithium hydroxide monohydrate / water; tetrahydrofuran / 5 h / 0 - 20 °C / Inert atmosphere

5: triethylamine; 1-hydroxy-7-aza-benzotriazole; HATU / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

6: dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

7: triethylamine; 1-hydroxy-7-aza-benzotriazole; HATU / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

8: hydrogenchloride; sodium hydrogencarbonate / water

9: lithium hydroxide / water; tetrahydrofuran / 72 h / 0 - 20 °C / Inert atmosphere

With hydrogenchloride; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1039/c3ob27111k

Reference yield:

: 13139-16-7
N-(tert-butyloxycarbonyl)-L-isoleucine

: 1427513-72-1
C₃₈H₅₁N₅O₆S

Guidance literature:: Multi-step reaction with 8 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / 0 - 20 °C

2: hydrogenchloride; sodium hydrogencarbonate / water

3: lithium hydroxide monohydrate / water; tetrahydrofuran / 5 h / 0 - 20 °C / Inert atmosphere

4: triethylamine; 1-hydroxy-7-aza-benzotriazole; HATU / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

5: dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

6: triethylamine; 1-hydroxy-7-aza-benzotriazole; HATU / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

7: hydrogenchloride; sodium hydrogencarbonate / water

8: lithium hydroxide / water; tetrahydrofuran / 72 h / 0 - 20 °C / Inert atmosphere

With hydrogenchloride; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1039/c3ob27111k