1-(4-Aminobenzyl)pyrimidine-2,4(1h,3h)-dione

Base Information

Chemical Name:1-(4-Aminobenzyl)pyrimidine-2,4(1h,3h)-dione
CAS No.:7292-94-6
Molecular Formula:C11H11 N3 O2
Molecular Weight:217.2239
Hs Code.:
NSC Number:110799
DSSTox Substance ID:DTXSID80296686
Wikidata:Q82037393

Synonyms:7292-94-6;1-(4-aminobenzyl)pyrimidine-2,4(1h,3h)-dione;NSC110799;SCHEMBL19370625;DTXSID80296686;NSC-110799

Suppliers and Price of 1-(4-Aminobenzyl)pyrimidine-2,4(1h,3h)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(4-Aminobenzyl)pyrimidine-2,4(1h,3h)-dione

Chemical Property:

Density:1.354g/cm³
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:217.085126602
Heavy Atom Count:16
Complexity:319

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CN2C=CC(=O)NC2=O)N

Technology Process of 1-(4-Aminobenzyl)pyrimidine-2,4(1h,3h)-dione

There total 3 articles about 1-(4-Aminobenzyl)pyrimidine-2,4(1h,3h)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 7263-86-7
1-(4-nitrobenzyl)uracil

: 7292-94-6
1-(4-aminobenzyl)pyrimidine-2,4-(1H,3H)dione

Guidance literature:: With tin(ll) chloride; In ethanol; at 70 ℃; for 2h;
DOI:10.1016/S0040-4020(02)01059-1

Reference yield:

: 100-11-8
1-bromomethyl-4-nitro-benzene

: 7292-94-6
1-(4-aminobenzyl)pyrimidine-2,4-(1H,3H)dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: hexamethyldisilazane; (NH₄)2SO₄ / 16 h / Heating

1.2: 48 percent / acetonitrile / 24 h / Heating

2.1: 78 percent / SnCl₂*2H₂O / ethanol / 2 h / 70 °C

With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane; tin(ll) chloride; In ethanol;
DOI:10.1016/S0040-4020(02)01059-1