cyclohexyl-oxiranylmethylene-amine oxide

Base Information

• Chemical Name: cyclohexyl-oxiranylmethylene-amine oxide
• CAS No.: 69739-33-9
• Molecular Formula: C₉H₁₅NO₂
• Molecular Weight: 169.224
• Mol file: 69739-33-9.mol

Synonyms:

Chemical Property of cyclohexyl-oxiranylmethylene-amine oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclohexyl-oxiranylmethylene-amine oxide

There total 1 articles about cyclohexyl-oxiranylmethylene-amine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ cyclohexyl-oxiranylmethylene-amine oxide (69739-33-9)

Guidance literature:

Epoxypropanal (15), CH2Cl2, N-Cyclohexyl-hydroxylamin, MgSO4;

DOI:10.1002/hlca.19790620129

Reference yield:

cyclohexyl-oxiranylmethylene-amine oxide (69739-33-9) → 3β-acetoxy-2'-cyclohexyl-4'ξ-hydroxymethyl-(5α,16β,17β)-tetrahydro-androstano[16,17-e][1,2]oxazine-3'ξ-carboxylic acid lactone (72166-17-7)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) CH₂Cl₂, (ii) /BRN= 4652394/, H₂O

2: urea*HF / propan-2-ol / 0 °C

3: Al₂O₃ / CH₂Cl₂

With aluminum oxide; urea hydrogen fluoride; In dichloromethane; isopropyl alcohol;

DOI:10.1002/hlca.19790620524

Reference yield:

cyclohexyl-oxiranylmethylene-amine oxide (69739-33-9) → 3β-acetoxy-2'-cyclohexyl-4'ξ-methanesulfonyloxymethyl-(5α,16β,17β)-tetrahydro-androstano[16,17-e][1,2]oxazine-3'ξ-carbonitrile (72166-32-6)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) CH₂Cl₂, (ii) /BRN= 4652394/, H₂O

2: urea*HF / propan-2-ol / 0 °C

3: Py / -14 °C

With pyridine; urea hydrogen fluoride; In isopropyl alcohol;

DOI:10.1002/hlca.19790620524

Downstream raw materials:

2-cyclohexyl-4ξ-hydroxymethyl-8a-methyl-(4ar,8ac)-octahydro-benzo[e][1,2]oxazine-3ξ-carbonitrile

2'-cyclohexyl-3β-methoxy-4'ξ-(trimethylsilanyloxy-methyl)-(5α,16β,17β)-tetrahydro-androstano[16,17-e][1,2]oxazine-3'ξ-carbonitrile

4'ξ-[(tert-butyl-dimethyl-silanyloxy)-methyl]-2'-cyclohexyl-3β-methoxy-(5α,16β,17β)-tetrahydro-androstano[17,16-e][1,2]oxazine-3'ξ-carbonitrile

4'ξ-[(tert-butyl-dimethyl-silanyloxy)-methyl]-2'-cyclohexyl-3β-methoxy-(5α,16β,17β)-tetrahydro-androstano[16,17-e][1,2]oxazine-3'ξ-carbonitrile