3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

Base Information

Chemical Name:3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate
CAS No.:134391-76-7
Molecular Formula:C9H12F3NO3SSi
Molecular Weight:299.346
Hs Code.:
European Community (EC) Number:808-421-9
DSSTox Substance ID:DTXSID60567705
Nikkaji Number:J3.048.401K
Wikidata:Q82453697
Mol file:134391-76-7.mol

Synonyms:3-(trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate;134391-76-7;(3-trimethylsilylpyridin-2-yl) trifluoromethanesulfonate;3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate 95%;C9H12F3NO3SSi;DTXSID60567705;SXIBFUWSBRRXRJ-UHFFFAOYSA-N;MFCD18257067;AKOS037646815;3-(trimethylsilyl)pyridin-2-yl triflate;AS-71025;3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate, 95%;3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate, AldrichCPR

Suppliers and Price of 3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:299.02592544
Heavy Atom Count:18
Complexity:385

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C1=C(N=CC=C1)OS(=O)(=O)C(F)(F)F

Technology Process of 3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

There total 5 articles about 3-(Trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 3-trimethylsilyl-2-hydroxypyridine

: 358-23-6
trifluoromethylsulfonic anhydride

: 134391-76-7
3-(trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

Guidance literature:: With pyridine; at 20 ℃;
DOI:10.1021/jm0704696

Reference yield: 93.0%

: 358-23-6
trifluoromethylsulfonic anhydride

: 17379-48-5
3-(trimethylsilyl)pyridin-2(1H)-one

: 134391-76-7
3-(trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

Guidance literature:: With 2,6-di-tert-butyl-4-methylpyridine; In dichloromethane; for 1h;
DOI:10.1080/00397919708007079

Reference yield:

: 142-08-5
2-hydroxypyridin

: 134391-76-7
3-(trimethylsilyl)pyridin-2-yl trifluoromethanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) LDA / 1.) Et₂O, hexane, 30 min, 2.) Et₂O, hexane, 17 h

2: 93 percent / 2,6-di-t-butyl-4-methylpyridine / CH₂Cl₂ / 1 h

With 2,6-di-tert-butyl-4-methylpyridine; lithium diisopropyl amide; In dichloromethane;
DOI:10.1080/00397919708007079