4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

Base Information

Chemical Name:4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole
CAS No.:131475-26-8
Molecular Formula:C₂₃H₃₀N₂O
Molecular Weight:350.504
Hs Code.:

Synonyms:

Suppliers and Price of 4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

There total 9 articles about 4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 131501-60-5
{2-[5-Benzyloxy-3-nitro-2-((E)-2-piperidin-1-yl-vinyl)-phenyl]-ethyl}-dipropyl-amine

: 131475-26-8
4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

Guidance literature:: With nickel boride (from Ni(AcO)2 + NaBH₄); hydrazine hydrate; In ethanol; for 2h; Yield given; Heating;

Reference yield:

: 131475-19-9
2-methyl-3-nitro-5-aminobenzyl alcohol

: 131475-26-8
4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) 20percent aq. H₂SO₄, aq. NaNO₂, 2.) 20percent aq. H₂SO₄ / 1.) from -5 to 0 deg C, 90 min, 2.) 90 deg C, 2 h

2: 71 percent / K₂CO₃ / acetone / 36 h / Heating

3: SOCl₂ / benzene / 6 h / Ambient temperature

4: 70 percent / dimethylsulfoxide / 3 h / Ambient temperature

5: NaBH₄, CF₃COOH / tetrahydrofuran / 4 h / Ambient temperature

6: 64 percent / aq. K₂CO₃ / benzene / 96 h / Heating

7: 36 h / 110 °C / 16 Torr

8: nickel boride (from Ni(AcO)2 + NaBH₄), NH₂NH₂*H₂O / ethanol / 2 h / Heating

With sodium tetrahydroborate; thionyl chloride; nickel boride (from Ni(AcO)2 + NaBH₄); sulfuric acid; potassium carbonate; hydrazine hydrate; trifluoroacetic acid; sodium nitrite; In tetrahydrofuran; ethanol; dimethyl sulfoxide; acetone; benzene;

Reference yield:

: 131475-20-2
2-methyl-3-nitro-5-hydroxybenzyl alcohol

: 131475-26-8
4-<2-(di-n-propylamino)ethyl>-6-benzyloxyindole

Guidance literature:: Multi-step reaction with 7 steps

1: 71 percent / K₂CO₃ / acetone / 36 h / Heating

2: SOCl₂ / benzene / 6 h / Ambient temperature

3: 70 percent / dimethylsulfoxide / 3 h / Ambient temperature

4: NaBH₄, CF₃COOH / tetrahydrofuran / 4 h / Ambient temperature

5: 64 percent / aq. K₂CO₃ / benzene / 96 h / Heating

6: 36 h / 110 °C / 16 Torr

7: nickel boride (from Ni(AcO)2 + NaBH₄), NH₂NH₂*H₂O / ethanol / 2 h / Heating

With sodium tetrahydroborate; thionyl chloride; nickel boride (from Ni(AcO)2 + NaBH₄); potassium carbonate; hydrazine hydrate; trifluoroacetic acid; In tetrahydrofuran; ethanol; dimethyl sulfoxide; acetone; benzene;