C₁₇H₁₇N₃O

Base Information

• Chemical Name: C₁₇H₁₇N₃O
• CAS No.: 1318245-07-6
• Molecular Formula: C₁₇H₁₇N₃O
• Molecular Weight: 279.341
• Mol file: 1318245-07-6.mol

Synonyms:

Chemical Property of C₁₇H₁₇N₃O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₇N₃O

There total 6 articles about C₁₇H₁₇N₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H10O + benzyl azide (622-79-7) → C17H17N3O (1318245-07-6)

Guidance literature:

With copper(ll) sulfate pentahydrate; isoascorbic acid; In water; N,N-dimethyl-formamide; at 20 ℃; for 0.666667h; Inert atmosphere;

DOI:10.1021/jo2008719

Reference yield:

C17H30OSi2 → C17H17N3O (1318245-07-6)

Guidance literature:

Multi-step reaction with 6 steps

1.1: carbon tetrabromide; triphenylphosphine / dichloromethane / Inert atmosphere

2.1: n-butyllithium / hexane / -78 - -20 °C / Inert atmosphere

3.1: methanol; potassium carbonate / tetrahydrofuran / 20 °C / Inert atmosphere

4.1: (1S,2R)-(+)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine / toluene / 0.33 h / 20 °C / Inert atmosphere

4.2: 35 h / 20 °C / Inert atmosphere

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 °C / Inert atmosphere

6.1: copper(ll) sulfate pentahydrate; isoascorbic acid / water; N,N-dimethyl-formamide / 0.67 h / 20 °C / Inert atmosphere

With methanol; n-butyllithium; copper(ll) sulfate pentahydrate; carbon tetrabromide; (1S,2R)-(+)-N-methylephedrine; tetrabutyl ammonium fluoride; zinc trifluoromethanesulfonate; potassium carbonate; triethylamine; triphenylphosphine; isoascorbic acid; In tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene; 2.1: Fritsch-Buttenberg-Wiechell rearrangement;

DOI:10.1021/jo2008719

Reference yield:

C18H30Br2Si2 → C17H17N3O (1318245-07-6)

Guidance literature:

Multi-step reaction with 5 steps

1.1: n-butyllithium / hexane / -78 - -20 °C / Inert atmosphere

2.1: methanol; potassium carbonate / tetrahydrofuran / 20 °C / Inert atmosphere

3.1: (1S,2R)-(+)-N-methylephedrine; zinc trifluoromethanesulfonate; triethylamine / toluene / 0.33 h / 20 °C / Inert atmosphere

3.2: 35 h / 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 °C / Inert atmosphere

5.1: copper(ll) sulfate pentahydrate; isoascorbic acid / water; N,N-dimethyl-formamide / 0.67 h / 20 °C / Inert atmosphere

With methanol; n-butyllithium; copper(ll) sulfate pentahydrate; (1S,2R)-(+)-N-methylephedrine; tetrabutyl ammonium fluoride; zinc trifluoromethanesulfonate; potassium carbonate; triethylamine; isoascorbic acid; In tetrahydrofuran; hexane; water; N,N-dimethyl-formamide; toluene; 1.1: Fritsch-Buttenberg-Wiechell rearrangement;

DOI:10.1021/jo2008719

upstream raw materials:

C₁₉H₃₀OSi

benzyl azide

1-(triisopropylsilyl)-6-(trimethylsilyl)-1,3,5-hexatriyne