5-Hydrazinylisoquinoline dihydrochloride

Base Information

• Chemical Name: 5-Hydrazinylisoquinoline dihydrochloride
• CAS No.: 102852-56-2
• Molecular Formula: C₉H₉N₃*2ClH
• Molecular Weight: 232.112
• European Community (EC) Number: 821-714-6
• Mol file: 102852-56-2.mol

Synonyms:5-hydrazinylisoquinoline dihydrochloride;102852-56-2;5-Hydrazinylisoquinoline diHCl;isoquinolin-5-ylhydrazine;dihydrochloride;CEA85256;MFCD27959471;5-hydrazinylisoquinolinedihydrochloride;AKOS026741524;BS-14277;CS-0160685;D80832;EN300-169918

Chemical Property of 5-Hydrazinylisoquinoline dihydrochloride

Chemical Property:

• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 231.0330028
• Heavy Atom Count: 14
• Complexity: 149

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC2=C(C=CN=C2)C(=C1)NN.Cl.Cl

Technology Process of 5-Hydrazinylisoquinoline dihydrochloride

There total 4 articles about 5-Hydrazinylisoquinoline dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

5-hydrazino-isoquinoline (90564-61-7) → 5-hydrazino-isoquinoline dihydrochloride (102852-56-2)

Guidance literature:

With hydrogenchloride; In ethanol;

Reference yield:

isoquinolin-5-ylamine (1125-60-6) → 5-hydrazino-isoquinoline dihydrochloride (102852-56-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) sodium nitrite, HCl; 2.) stannous chloride dihydrate, HCl / 1.) H₂O; 2.) H₂O

2: 90 percent / hydrogen chloride gas / ethanol

With hydrogenchloride; tin(ll) chloride; sodium nitrite; In ethanol;

Reference yield:

isoquinolin-5-yldiazonium chloride → isoquinolin-5-ylhydrazinium chloride (102852-56-2)

Guidance literature:

With tin(ll) chloride;

DOI:10.1002/jhet.1735

upstream raw materials:

5-hydrazino-isoquinoline

isoquinolin-5-ylamine

Downstream raw materials:

3-(4-Nitrophenylazo)-1H-Pyrrolo<2,3-f>isoquinoline

3,3-dimethyl-2-(1-phenyl-1H-pyrazol-4-yl)-3H-pyrrolo[2,3-f]isoquinoline

2-(1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,3-dimethyl-3H-pyrrolo[2,3-f]isoquinoline

2-(1-(3-chlorophenyl)-1H-pyrazol-4-yl)-3,3-dimethyl-3H-pyrrolo[2,3-f]isoquinoline