Technology Process of rac-9,10-methanediyldioxy-galantha-2,4(12)-dien-7-one
There total 7 articles about rac-9,10-methanediyldioxy-galantha-2,4(12)-dien-7-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1H-imidazole / dichloromethane / 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran / Inert atmosphere
3.1: 5 h / 200 °C / Inert atmosphere; Microwave irradiation
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / Inert atmosphere
4.2: Inert atmosphere
5.1: trifluoromethylsulfonic anhydride; dmap / Inert atmosphere
With
1H-imidazole; dmap; trifluoromethylsulfonic anhydride; tetrabutyl ammonium fluoride; sodium hydride;
In
tetrahydrofuran; dichloromethane;
4.1: |Mitsunobu Displacement / 5.1: |Bischler-Napieralski Reaction;
DOI:10.1021/ol303157b
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran / Inert atmosphere
2.1: 5 h / 200 °C / Inert atmosphere; Microwave irradiation
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / Inert atmosphere
3.2: Inert atmosphere
4.1: trifluoromethylsulfonic anhydride; dmap / Inert atmosphere
With
dmap; trifluoromethylsulfonic anhydride; tetrabutyl ammonium fluoride; sodium hydride;
In
tetrahydrofuran;
3.1: |Mitsunobu Displacement / 4.1: |Bischler-Napieralski Reaction;
DOI:10.1021/ol303157b
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 5 h / 200 °C / Inert atmosphere; Microwave irradiation
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / Inert atmosphere
2.2: Inert atmosphere
3.1: trifluoromethylsulfonic anhydride; dmap / Inert atmosphere
With
dmap; trifluoromethylsulfonic anhydride; tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
2.1: |Mitsunobu Displacement / 3.1: |Bischler-Napieralski Reaction;
DOI:10.1021/ol303157b
