Phe-D-Pro-Pro-OBn hydrochloride

Base Information

• Chemical Name: Phe-D-Pro-Pro-OBn hydrochloride
• CAS No.: 103126-95-0
• Molecular Formula: C₂₆H₃₁N₃O₄*ClH
• Molecular Weight: 486.011
• Mol file: 103126-95-0.mol

Synonyms:

Chemical Property of Phe-D-Pro-Pro-OBn hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phe-D-Pro-Pro-OBn hydrochloride

There total 5 articles about Phe-D-Pro-Pro-OBn hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc-Phe-D-Pro-Pro-OBn (88501-11-5) → Phe-D-Pro-Pro-OBn hydrochloride (103126-95-0)

Guidance literature:

With hydrogenchloride; In acetic acid;

DOI:10.1021/jm00092a008

Reference yield:

benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride (16652-71-4) → Phe-D-Pro-Pro-OBn hydrochloride (103126-95-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 95 percent / dicyclohexylcarbodiimide (DCC), 1-hydroxybenzotriazole (HOBT), Et₃N / dimethylformamide / 144 h / 5 °C

2: HCl / acetic acid

4: HCl / acetic acid

With hydrogenchloride; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In acetic acid; N,N-dimethyl-formamide;

DOI:10.1021/jm00092a008

Reference yield:

Boc-D-Pro-Pro-OBn (141636-70-6) → Phe-D-Pro-Pro-OBn hydrochloride (103126-95-0)

Guidance literature:

Multi-step reaction with 3 steps

1: HCl / acetic acid

3: HCl / acetic acid

With hydrogenchloride; In acetic acid;

DOI:10.1021/jm00092a008

upstream raw materials:

Boc-Phe-D-Pro-Pro-OBn

benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride

Boc-D-Pro-Pro-OBn

D-Pro-Pro-OBn hydrochloride