(S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester

Base Information

Chemical Name:(S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester
CAS No.:546113-70-6
Molecular Formula:C₃₈H₃₇N₄O₁₄P
Molecular Weight:804.704
Hs Code.:

(S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester

Synonyms:

Suppliers and Price of (S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester

There total 2 articles about (S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 129902-07-4
L-aspartic acid β-methyl ester hydrochloride

: 546113-65-9
C₃₃H₃₀N₃O₁₀P

: 546113-70-6
(S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester

Guidance literature:: With triethylamine; In tetrachloromethane; dichloromethane; at 20 ℃;
DOI:10.1016/S0960-894X(02)00735-7

Reference yield:

: 302346-91-4
3-propenyl-(2',3'-O,N⁴-tribenzoyl cytidine-5')-yl-N,N'-diisopropylphosphoramidite

: 546113-70-6
(S)-2-{Allyloxy-[(2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-3,4-bis-benzoyloxy-tetrahydro-furan-2-ylmethoxy]-phosphorylamino}-succinic acid 1-methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / tetrazole; H₂O / acetonitrile / 20 °C

2: Et₃N / CCl₄; CH₂Cl₂ / 20 °C

With 1H-tetrazole; water; triethylamine; In tetrachloromethane; dichloromethane; acetonitrile; 2: Atherton-Todd reaction;
DOI:10.1016/S0960-894X(02)00735-7