6-chloro-9-purine

Base Information

• Chemical Name: 6-chloro-9-purine
• CAS No.: 137171-59-6
• Molecular Formula: C₂₅H₃₄ClN₅O₄
• Molecular Weight: 504.029

Synonyms:

Chemical Property of 6-chloro-9-purine

Chemical Property:

Purity/Quality:

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Technology Process of 6-chloro-9-purine

There total 1 articles about 6-chloro-9-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

methanetricarboxylic acid triethyl ester (6279-86-3) + 2,5,6-triamino-4-chloro-N6-pyrimidine (132332-75-3,137171-58-5) → 6-chloro-9-purine (132332-77-5,137171-59-6)

Guidance literature:

With hydrogenchloride; for 3h; Ambient temperature;

DOI:10.1248/cpb.38.2719

Reference yield: 61.0%

6-chloro-9-purine (132332-77-5,137171-59-6) → 9-guanine (126062-18-8,126373-87-3,127759-89-1,129261-93-4,130464-69-6,130466-27-2,132077-79-3)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; for 3h; Ambient temperature;

DOI:10.1248/cpb.38.2719

upstream raw materials:

methanetricarboxylic acid triethyl ester

2,5,6-triamino-4-chloro-N⁶-pyrimidine

Downstream raw materials:

9-guanine

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