4-hydroxytoremifene quinone methide

Base Information

• Chemical Name: 4-hydroxytoremifene quinone methide
• CAS No.: 259087-27-9
• Molecular Formula: C₂₆H₂₆ClNO₂
• Molecular Weight: 419.951
• Mol file: 259087-27-9.mol

Synonyms:

Chemical Property of 4-hydroxytoremifene quinone methide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-hydroxytoremifene quinone methide

There total 1 articles about 4-hydroxytoremifene quinone methide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-4-Hydroxytoremifene (110503-62-3,177748-22-0) → 4-hydroxytoremifene quinone methide (259087-27-9)

Guidance literature:

With manganese(IV) oxide; In acetone; at 0 - 5 ℃; for 1h;

DOI:10.1021/tx990144v

Reference yield:

GLUTATHIONE (70-18-8) + 4-hydroxytoremifene quinone methide (259087-27-9) → 2-amino-4-[2-[1-[2-(4-amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethylsulfanylmethyl]-3-[4-(2-dimethylamino-ethoxy)-phenyl]-3-(4-hydroxy-phenyl)-2-phenyl-allylsulfanyl]-1-(carboxymethyl-carbamoyl)-ethylcarbamoyl]-butyric acid

Guidance literature:

In phosphate buffer; pH=7.4;

DOI:10.1021/tx990144v

upstream raw materials:

(Z)-4-Hydroxytoremifene