4-Methoxycinnamamide

Base Information

Chemical Name:4-Methoxycinnamamide
CAS No.:18166-63-7
Molecular Formula:C₁₀H₁₁NO₂
Molecular Weight:177.203
Hs Code.:
NSC Number:26472
DSSTox Substance ID:DTXSID80358894
Nikkaji Number:J2.248.177K,J370.610I
Wikidata:Q82139798

Synonyms:NSC26472;18166-63-7;3-(p-methoxyphenyl)acrylamide;3-(4-methoxy-phenyl)acrylamide;DTXSID80358894;NSC-26472;AKOS003418321

Suppliers and Price of 4-Methoxycinnamamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-Methoxycinnamamide

Chemical Property:

Vapor Pressure:8.76E-07mmHg at 25°C
Boiling Point:405.5°C at 760 mmHg
Flash Point:235.7°C
Density:1.141g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=CC(=O)N
Isomeric SMILES:COC1=CC=C(C=C1)/C=C/C(=O)N

Technology Process of 4-Methoxycinnamamide

There total 23 articles about 4-Methoxycinnamamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 830-09-1
3-(4'-methoxyphenyl)propenoic acid

: 36650-51-8,18166-63-7
4-methoxycinnamic acid amide

Guidance literature:: 3-(4'-methoxyphenyl)propenoic acid; With oxalyl dichloride; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 3.25h;

With ammonia; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); water; at 0 - 5 ℃; for 0.75h;

Reference yield: 93.0%

: 104-92-7
1-bromo-4-methoxy-benzene

: 79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5
2-propenamide

: 36650-51-8,18166-63-7
(2E)-3-(4-methoxyphenyl)acrylamide

Guidance literature:: With 2Br^(1-)*C₄₆H₄₈N₄O₂⁽²⁺⁾; palladium diacetate; sodium carbonate; In N,N-dimethyl acetamide; at 140 ℃; for 10h; stereoselective reaction; Inert atmosphere;
DOI:10.1007/s11426-011-4272-4