4-Morpholinecarboxylic acid, 2-[(phenylmethoxy)methyl]-, 1,1-dimethylethyl ester, (2R)-

Base Information

Chemical Name:4-Morpholinecarboxylic acid, 2-[(phenylmethoxy)methyl]-, 1,1-dimethylethyl ester, (2R)-
CAS No.:135097-68-6
Molecular Formula:C17H25NO4
Molecular Weight:307.39
Hs Code.:
Mol file:135097-68-6.mol

Synonyms:tert-butyl (R)-2-((benzyloxy)methyl)morpholine-4-carboxylate;2R-benzyloxymethyl-morpholine-4-carboxylic acid tert-butyl ester;(R)-2-benzyloxymethylmorpholine-4-carboxylic acid tert-butyl ester;(2R)-benzyloxymethyl-morpholine-4-carboxylic acid tert-butyl ester;(R)-2-benzyloxymethyl-morpholine-4-carboxylic acid tert-butyl ester;(R)-2-(benzyloxymethyl)morpholine-4-carboxylic acid tert-butyl ester;

Suppliers and Price of 4-Morpholinecarboxylic acid, 2-[(phenylmethoxy)methyl]-, 1,1-dimethylethyl ester, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-tert-Butyl2-((benzyloxy)methyl)morpholine-4-carboxylate 97%
5g
$ 2143.00

Crysdot
(R)-tert-Butyl2-((benzyloxy)methyl)morpholine-4-carboxylate 97%
1g
$ 713.00

Total 6 raw suppliers

Chemical Property of 4-Morpholinecarboxylic acid, 2-[(phenylmethoxy)methyl]-, 1,1-dimethylethyl ester, (2R)-

Chemical Property:

PSA：48.00000
LogP:2.77700

Purity/Quality:

99% ^*data from raw suppliers

(R)-tert-Butyl2-((benzyloxy)methyl)morpholine-4-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Morpholinecarboxylic acid, 2-[(phenylmethoxy)methyl]-, 1,1-dimethylethyl ester, (2R)-

There total 3 articles about 4-Morpholinecarboxylic acid, 2-[(phenylmethoxy)methyl]-, 1,1-dimethylethyl ester, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 135065-70-2
(2R)-2-[(benzyloxy)methyl]morpholine

: 135097-68-6
tert-butyl (2R)-2-[(benzyloxy)methyl]morpholine-4-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 20 - 25 ℃; for 2h;

Reference yield:

: 14618-80-5
(R)-benzyl glycidol

: 135097-68-6
tert-butyl (2R)-2-[(benzyloxy)methyl]morpholine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / NaOH / H₂O / 21 h / 50 - 55 °C

2: 88 percent / Et₃N / CH₂Cl₂ / 2 h / 20 - 25 °C

With sodium hydroxide; triethylamine; In dichloromethane; water;

Reference yield:

: C₁₂H₁₉NO₆S

: 135097-68-6
tert-butyl (2R)-2-[(benzyloxy)methyl]morpholine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water; toluene / 16 h / 65 °C

2: potassium carbonate / water; acetone / 0.5 h / 0 - 20 °C

With potassium carbonate; sodium hydroxide; In water; acetone; toluene;
DOI:10.1016/j.bmcl.2011.06.043