Technology Process of C39H47ClN4O4S
There total 7 articles about C39H47ClN4O4S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)benzoic acid;
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
dichloromethane; N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
Inert atmosphere;
C15H26N2O3S;
In
dichloromethane; N,N-dimethyl-formamide;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/ml300095a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: zinc(II) chloride / diethyl ether; 1,2-dichloro-ethane / 12 h / 90 °C / Inert atmosphere
2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane; N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; zinc(II) chloride;
In
diethyl ether; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
1.1: Ritter reaction;
DOI:10.1021/ml300095a
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sulfuryl dichloride; acetic anhydride / 1,2-dichloro-ethane / 0.5 h / -10 °C / Inert atmosphere
1.2: Inert atmosphere; Cooling with ice
2.1: potassium permanganate / water; acetone / 2 h / 50 °C / Inert atmosphere
3.1: zinc(II) chloride / diethyl ether; 1,2-dichloro-ethane / 12 h / 90 °C / Inert atmosphere
4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane; N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere
4.2: 20 °C / Inert atmosphere
With
potassium permanganate; sulfuryl dichloride; acetic anhydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; zinc(II) chloride;
In
diethyl ether; dichloromethane; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetone;
3.1: Ritter reaction;
DOI:10.1021/ml300095a