Imidafenacin metabolite M4

Base Information

Chemical Name:Imidafenacin metabolite M4
CAS No.:503598-17-2
Molecular Formula:C₁₈H₁₉N₃O₃
Molecular Weight:325.367
Hs Code.:
UNII:M6F15S6RGI
Nikkaji Number:J2.473.319J
Mol file:503598-17-2.mol

Synonyms:503598-17-2;Imidafenacin metabolite M4;UNII-M6F15S6RGI;M6F15S6RGI;N'-(4-amino-4-oxo-3,3-diphenylbutyl)oxamide;N-(3-Carbamoyl-3,3-diphenylpropyl)oxamide;N1-(4-Amino-4-oxo-3,3-diphenylbutyl)ethanediamide;Ethanediamide, N1-(4-amino-4-oxo-3,3-diphenylbutyl)-;IMidafenacin Related CoMpound 2 (N-(3-CarbaMoyl-3,3-Diphenylpropyl)-OxaMide);N-(3-Carbamoyl-3,3-Diphenylpropyl)-Oxamide;AKOS040755396

Suppliers and Price of Imidafenacin metabolite M4

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of Imidafenacin metabolite M4

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:325.14264148
Heavy Atom Count:24
Complexity:448

Purity/Quality:: > 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(CCNC(=O)C(=O)N)(C2=CC=CC=C2)C(=O)N

Technology Process of Imidafenacin metabolite M4

There total 4 articles about Imidafenacin metabolite M4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 503598-78-5
4-amino-2-diphenylbutanamide

: 471-47-6
oxamic acid

: 503598-17-2
N-(3-carbamoyl-3,3-diphenylpropyl)oxamide

Guidance literature:: With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2.5h;
DOI:10.1248/cpb.55.1039

Reference yield:

: 503598-74-1
C₃₀H₃₀N₂O

: 503598-17-2
N-(3-carbamoyl-3,3-diphenylpropyl)oxamide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Perlman's catalyst

2: 35 percent / 1-hydroxybenzotriazole monohydrate; Et₃N; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / dimethylformamide / 2.5 h / 20 °C

With hydrogen; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium hydroxide - carbon; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.55.1039

Reference yield:

: 86-29-3
Diphenylacetonitrile

: 503598-17-2
N-(3-carbamoyl-3,3-diphenylpropyl)oxamide

Guidance literature:: Multi-step reaction with 4 steps

1: NaH / dimethylformamide

2: aq. KOH / propan-2-ol

3: H₂ / Perlman's catalyst

4: 35 percent / 1-hydroxybenzotriazole monohydrate; Et₃N; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / dimethylformamide / 2.5 h / 20 °C

With potassium hydroxide; hydrogen; sodium hydride; 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium hydroxide - carbon; In N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1248/cpb.55.1039