Methyl 2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrole-3-carboxylate

Base Information

Chemical Name:Methyl 2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrole-3-carboxylate
CAS No.:120943-16-0
Molecular Formula:C₁₂H₉NO₄
Molecular Weight:231.208
Hs Code.:
DSSTox Substance ID:DTXSID501179405

Synonyms:SCHEMBL3277570;DTXSID501179405;Methyl 2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrole-3-carboxylate;120943-16-0

Suppliers and Price of Methyl 2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrole-3-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrole-3-carboxylate

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:231.05315777
Heavy Atom Count:17
Complexity:393

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC(=O)N(C1=O)C2=CC=CC=C2

Technology Process of Methyl 2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrole-3-carboxylate

There total 5 articles about Methyl 2,5-dihydro-2,5-dioxo-1-phenyl-1H-pyrrole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.2%

: 120943-15-9
(1R,2R,6S,7S)-3,5-Dioxo-4-phenyl-4-aza-tricyclo[5.2.1.0^2,6]dec-8-ene-2-carboxylic acid methyl ester

: 120943-16-0
α-carbomethoxy-N-phenylmaleimide

Guidance literature:: In benzene; at 650 ℃;
DOI:10.1021/jo00273a014

Reference yield:

: 51175-48-5
ethene-1,1,2-tricarboxylic acid trimethyl ester

: 120943-16-0
α-carbomethoxy-N-phenylmaleimide

Guidance literature:: Multi-step reaction with 5 steps

1: 73 percent / P₂O₅ / 5 h / 155 - 160 °C

2: 78.3 percent / CH₂Cl₂ / 3 h / Ambient temperature

3: 88.5 percent / diethyl ether / 20 h / 28 °C

4: 96.9 percent / trifluoroacetic anhydride / CH₂Cl₂ / 6 h / 0 °C

5: 19.2 percent / benzene / 650 °C

With phosphorus pentoxide; trifluoroacetic anhydride; In diethyl ether; dichloromethane; benzene;
DOI:10.1021/jo00273a014

Reference yield:

: 120943-14-8
norbornene amic acid

: 120943-16-0
α-carbomethoxy-N-phenylmaleimide

Guidance literature:: Multi-step reaction with 2 steps

1: 96.9 percent / trifluoroacetic anhydride / CH₂Cl₂ / 6 h / 0 °C

2: 19.2 percent / benzene / 650 °C

With trifluoroacetic anhydride; In dichloromethane; benzene;
DOI:10.1021/jo00273a014