5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

Base Information

Chemical Name:5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
CAS No.:1416324-85-0
Molecular Formula:C₁₉H₂₂O₇
Molecular Weight:362.379
Hs Code.:
Mol file:1416324-85-0.mol

Synonyms:

Suppliers and Price of 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
CUCPT22
1mg
$ 160.00

Tocris
CUCPT22 ≥98%(HPLC)
10
$ 266.00

Tocris
CUCPT22 ≥98%(HPLC)
50
$ 1055.00

ChemScene
CU-CPT22 >99.0%
25mg
$ 420.00

ChemScene
CU-CPT22 >99.0%
10mg
$ 220.00

ChemScene
CU-CPT22 >99.0%
5mg
$ 130.00

Cayman Chemical
CU CPT 22
5mg
$ 124.00

Cayman Chemical
CU CPT 22
1mg
$ 45.00

Cayman Chemical
CU CPT 22
10mg
$ 225.00

ApexBio Technology
CUCPT22
5mg
$ 189.00

Total 22 raw suppliers

Chemical Property of 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

Chemical Property:

Boiling Point:610.4±55.0 °C(Predicted)
PKA:6.04±0.20(Predicted)
Density:1.336±0.06 g/cm3(Predicted)
Storage Temp.:2-8°C
Solubility.:DMSO: soluble20mg/mL, clear

Purity/Quality:

99%, ^*data from raw suppliers

CUCPT22 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:N
Statements: 50/53
Safety Statements: 60-61

MSDS Files:

Useful:

Description CU CPT 22 is an antagonist of toll-like receptor 1 (TLR1) and TLR2 heterodimers (TLR1/TLR2; Ki = 0.41 μM). It inhibits nitric oxide (NO) production induced by the TLR2 agonist Pam3CSK4 in RAW 264.7 cells (IC50 = 0.58 μM). It is selective for TLR1/TLR2 over TLR2/TLR6 and TLR3, -4, and -7 homodimers, as well as 10 kinases at 0.5 μM. CU CPT 22 (8 μM) inhibits Pam3CSK4-induced release of TNF-α and IL-1β in RAW 264.7 cells by 60 and 95%, respectively.

Technology Process of 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

There total 3 articles about 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 934-00-9
3-methocycatechol

: 1087-26-9
n-hexyl gallate

: 1416324-85-0
CU-CPT22

Guidance literature:: With dihydrogen peroxide; horseradish peroxidase; In aq. phosphate buffer; acetone; pH=5;
DOI:10.1002/anie.201204910

Reference yield: 54.0%

: 1416324-85-0
CU-CPT22

Guidance literature:: With dihydrogen peroxide; horseradish peroxidase; In acetone; pH=5.0;

Reference yield:

: 111-27-3
hexan-1-ol

: 1416324-85-0
CU-CPT22

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / Reflux

2: dihydrogen peroxide; horseradish peroxidase / acetone; aq. phosphate buffer / pH 5

With sulfuric acid; dihydrogen peroxide; horseradish peroxidase; In aq. phosphate buffer; acetone;
DOI:10.1002/anie.201204910