16-epigardnerine

Base Information

• Chemical Name: 16-epigardnerine
• CAS No.: 69830-86-0
• Molecular Formula: C₂₀H₂₄N₂O₂
• Molecular Weight: 324.423
• Mol file: 69830-86-0.mol

Synonyms:

Chemical Property of 16-epigardnerine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 16-epigardnerine

There total 4 articles about 16-epigardnerine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

gardnerine (23172-92-1,69830-86-0) → 16-epigardnerine (23172-92-1,69830-86-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 46 percent / N-chlorosuccinimide (NCS), Me₂S / toluene; dimethylformamide / 5 h / -27 - -20 °C

2: NaBH₄ / methanol / 3 h / Ambient temperature

With sodium tetrahydroborate; N-chloro-succinimide; dimethylsulfide; In methanol; N,N-dimethyl-formamide; toluene;

Reference yield:

16-epigardneral (73748-86-4,112459-11-7) → 16-epigardnerine (23172-92-1,69830-86-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 3h; Ambient temperature;

Reference yield:

gardneral (73748-86-4,112459-11-7) → 16-epigardnerine (23172-92-1,69830-86-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.1 N KOH / methanol / 5 h / Ambient temperature

2: NaBH₄ / methanol / 3 h / Ambient temperature

With potassium hydroxide; sodium tetrahydroborate; In methanol;

upstream raw materials:

Gardneral

16-epigardneral

gardneral

gardnerine

Downstream raw materials:

16-epigardnerine

Refernces

• 1、 Wan, Alfred S. C.,Yokota, Masaki,Ogata, Koreharu,Aimi, Norio,Sakai, Shin-ichiro. "STRUCTURE OF PELIRINE AND CHEMICAL CONVERSION OF GARDNERINE TO 11-METHOXY-16-EPIAFFININE". . p. 1211 - 1214. Retrieved 2007/10/02.