3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole

Base Information

• Chemical Name: 3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole
• CAS No.: 1632372-11-2
• Molecular Formula: C₄₄H₅₅N₃S₄
• Molecular Weight: 754.205
• Mol file: 1632372-11-2.mol

Synonyms:

Chemical Property of 3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole

There total 4 articles about 3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-decyl-N-phenyl-2,2'-bithiophene-5-carboxamide (1637596-36-1) → 3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole (1632372-11-2)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphorus pentachloride / benzene / 12 h / 20 °C / Cooling with ice

2: N,N-dimethyl acetamide / 6 h / 165 °C / Inert atmosphere

With phosphorus pentachloride; In N,N-dimethyl acetamide; benzene;

DOI:10.3762/bjoc.10.165

Reference yield:

3-decyl-2,2'-bithiophene-5-carboxylic acid chloride (1637596-38-3) → 3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole (1632372-11-2)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / ethyl acetate / 20 °C

2: phosphorus pentachloride / benzene / 12 h / 20 °C / Cooling with ice

3: N,N-dimethyl acetamide / 6 h / 165 °C / Inert atmosphere

With phosphorus pentachloride; triethylamine; In N,N-dimethyl acetamide; ethyl acetate; benzene;

DOI:10.3762/bjoc.10.165

Reference yield:

3-decyl(2,2'-bithiophene)-5-carboxylic acid (1416276-26-0) → 3,5-bis(3-decyl-2,2'-bithiophen-5-yl)-4-phenyl-4H-1,2,4-triazole (1632372-11-2)

Guidance literature:

Multi-step reaction with 4 steps

1: oxalyl dichloride / dichloromethane / 0 - 20 °C

2: triethylamine / ethyl acetate / 20 °C

3: phosphorus pentachloride / benzene / 12 h / 20 °C / Cooling with ice

4: N,N-dimethyl acetamide / 6 h / 165 °C / Inert atmosphere

With oxalyl dichloride; phosphorus pentachloride; triethylamine; In dichloromethane; N,N-dimethyl acetamide; ethyl acetate; benzene;

DOI:10.3762/bjoc.10.165

upstream raw materials:

3-decyl-N-phenyl-2,2'-bithiophene-5-carboxamide

3-decyl-N-phenyl-2,2'-bithiophene-5-carboximidoyl chloride

3-decyl-[2,2'-bithiophene]-5-carbohydrazide

3-decyl-2,2'-bithiophene-5-carboxylic acid chloride