β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol

Base Information

• Chemical Name: β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol
• CAS No.: 107913-79-1
• Molecular Formula: C₃₄H₅₈O₉Si₂
• Molecular Weight: 667
• Mol file: 107913-79-1.mol

Synonyms:

Chemical Property of β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol

There total 1 articles about β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-<2-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-2-propenyl>-3,5-dimethoxy-4-(3-methyl-2-butenyl)phenol acetate (107913-78-0) → 2-{2-[2,4-Bis-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-3-hydroxy-propyl}-3,5-dimethoxy-4-(3-methyl-but-2-enyl)-phenol + β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol (107913-79-1,107913-90-6)

Guidance literature:

With 9-borabicyclo[3.3.1]nonane dimer; In tetrahydrofuran; at 20 ℃; for 17h;

DOI:10.1021/jo00386a024

Reference yield: 83.0%

β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol (107913-79-1,107913-90-6) → <<4-<3,4-dihydro-5,7-dimethoxy-6-(3-methyl-2-butenyl)-2H-1-benzopyran-3-yl>-1,3-phenylene>bis<<(oxymethylene)oxy>-2,1-ethanediyl>>bis(trimethylsilane) (107913-82-6)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 22h;

DOI:10.1021/jo00386a024

Reference yield:

β-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-6-hydroxy-3-(2-hydroxy-3-methylbutyl)-2,4-dimethoxybenzenepropanol (107913-79-1,107913-90-6) → Glyasperin D (107913-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 22 h / 20 °C

2: 90 percent / conc. H₂SO₄ / methanol; tetrahydrofuran / 2 h / 20 °C

With sulfuric acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol;

DOI:10.1021/jo00386a024

upstream raw materials:

2-<2-<2,4-bis<<2-(trimethylsilyl)ethoxy>methoxy>phenyl>-2-propenyl>-3,5-dimethoxy-4-(3-methyl-2-butenyl)phenol acetate

Downstream raw materials:

<<4-<3,4-dihydro-5,7-dimethoxy-6-(3-methyl-2-butenyl)-2H-1-benzopyran-3-yl>-1,3-phenylene>bis<<(oxymethylene)oxy>-2,1-ethanediyl>>bis(trimethylsilane)

Glyasperin D

2-<3,4-dihydro-5,7-dimethoxy-6-(3-methyl-2-butenyl)-2H-1-benzopyran-3-yl>-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>phenol

(+/-)-5-O-methyllicoricidin