8(5H)-Isoquinolinone, 6,7-dihydro-, hydrochloride

Base Information

• Chemical Name: 8(5H)-Isoquinolinone, 6,7-dihydro-, hydrochloride
• CAS No.: 135311-97-6
• Molecular Formula: C₉H₉NO*ClH
• Molecular Weight: 183.637
• Hs Code.: 2933499090
• Mol file: 135311-97-6.mol

Synonyms:6,7-Dihydroisoquinolin-8(5H)-one hydrochloride;6,7-dihydro-5H-isoquinolin-8-one,hydrochloride;6,7-Dihydro-5H-isochinolin-8-on,Hydrochlorid;

Chemical Property of 8(5H)-Isoquinolinone, 6,7-dihydro-, hydrochloride

Chemical Property:

• Melting Point: 227-229 °C
• PSA: 29.96000
• LogP: 2.40260
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98.5% ^*data from raw suppliers

6,7-Dihydro-5H-isoquinolin-8-onehydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8(5H)-Isoquinolinone, 6,7-dihydro-, hydrochloride

There total 1 articles about 8(5H)-Isoquinolinone, 6,7-dihydro-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,6,7,8-tetrahydroisoquinoline (36556-06-6) → 7,8-dihydroisoquinolin-5(6H)-one (21917-86-2) + 5,6,7,8-tetrahydroisoquinolin-8-one hydrochloride (135311-97-6)

Guidance literature:

With potassium permanganate; In water; acetic acid; for 0.583333h;

DOI:10.1021/jm00074a019

Reference yield: 39.0%

2-[1-(triphenylmethyl)-1H-imidazol-4-yl]benzaldehyde (1402838-08-7) + 5,6,7,8-tetrahydroisoquinolin-8-one hydrochloride (135311-97-6) → 7-([2-[1-(triphenylmethyl)-1H-imidazol-4-yl]phenyl]methylidene)-5,6,7,8-tetrahydroisoquinolin-8-one

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 6h;

upstream raw materials:

5,6,7,8-tetrahydroisoquinoline

Refernces