octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside

Base Information

• Chemical Name: octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside
• CAS No.: 151902-35-1
• Molecular Formula: C₆₁H₈₁NO₂₂
• Molecular Weight: 1180.31
• Mol file: 151902-35-1.mol

Synonyms:

Chemical Property of octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside

There total 2 articles about octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

octyl 2,3,4-tri-O-benzyl-β-D-glucopyranoside (118249-72-2) + 2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl chloride (151902-33-9) → octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside (151902-35-1)

Guidance literature:

With 4 A molecular sieve; mercury(II) cyanide; mercury dibromide; In nitromethane; benzene; 1.) room temperature, 16 h, 2.) 40 deg C;

DOI:10.1016/0008-6215(93)80081-O

Reference yield:

2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-1,3,4,6-tetra-O-acetyl-α-D-mannopyranose (126354-03-8) → octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside (151902-35-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / HCl, Ac₂O / CH₂Cl₂ / 16 h / Ambient temperature

2: 51 percent / HgBr₂, Hg(CN)2, 4 Angstroem molecular sieves / benzene; nitromethane / 1.) room temperature, 16 h, 2.) 40 deg C

With hydrogenchloride; 4 A molecular sieve; mercury(II) cyanide; acetic anhydride; mercury dibromide; In nitromethane; dichloromethane; benzene;

DOI:10.1016/0008-6215(93)80081-O

Reference yield: 95.0%

octyl 6-O-<2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside (151902-35-1) → octyl 6-O-<2-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-α-D-mannopyranosyl>-2,3,4-tri-O-benzyl-β-D-glucopyranoside

Guidance literature:

With methanol; sodium methylate; for 16h; Ambient temperature;

DOI:10.1016/0008-6215(93)80081-O

upstream raw materials:

octyl 2,3,4-tri-O-benzyl-β-D-glucopyranoside

2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-3,4,6-tri-O-acetyl-α-D-mannopyranosyl chloride

2-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-1,3,4,6-tetra-O-acetyl-α-D-mannopyranose