Diethyl [amino(4-fluorophenyl)methyl]phosphonate

Base Information

Chemical Name:Diethyl [amino(4-fluorophenyl)methyl]phosphonate
CAS No.:135473-59-5
Molecular Formula:C11H17FNO3P
Molecular Weight:261.233
Hs Code.:
DSSTox Substance ID:DTXSID40573420
Nikkaji Number:J1.614.525D
Mol file:135473-59-5.mol

Synonyms:135473-59-5;Diethyl [amino(4-fluorophenyl)methyl]phosphonate;DTXSID40573420

Suppliers and Price of Diethyl [amino(4-fluorophenyl)methyl]phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Diethyl [amino(4-fluorophenyl)methyl]phosphonate

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:261.09300856
Heavy Atom Count:17
Complexity:259

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOP(=O)(C(C1=CC=C(C=C1)F)N)OCC

Technology Process of Diethyl [amino(4-fluorophenyl)methyl]phosphonate

There total 11 articles about Diethyl [amino(4-fluorophenyl)methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 135473-48-2
O,O-diethyl-N-benzylamino-4-fluorophenylmethylphosphonate

: 135473-59-5
α-O,O'-diethyl amino(4-fluorophenyl)methylphosphonate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 - 25 ℃; for 30h; under 760 Torr;

Reference yield: 76.0%

: 459-57-4
4-fluorobenzaldehyde

: 762-04-9
phosphonic acid diethyl ester

: 135473-59-5
α-O,O'-diethyl amino(4-fluorophenyl)methylphosphonate

Guidance literature:: With aluminum oxide; ammonium formate; at 20 ℃; for 8h;
DOI:10.1016/S0040-4039(01)01627-6

Reference yield: 55.0%

Diethyl phosphonate: 762-04-9,123-22-8
Diethyl phosphonate

: 459-57-4
4-fluorobenzaldehyde

: 135473-59-5
α-O,O'-diethyl amino(4-fluorophenyl)methylphosphonate

Guidance literature:: Diethyl phosphonate; 4-fluorobenzaldehyde; With ammonium acetate; at 60 - 80 ℃; for 12h;

With hydrogenchloride; In diethyl ether; for 2h; Cooling with ice;
DOI:10.2174/1570180812666141125004502