4-(Quinazolin-4-ylamino)benzoic acid

Base Information

Chemical Name:4-(Quinazolin-4-ylamino)benzoic acid
CAS No.:33683-30-6
Molecular Formula:C₁₅H₁₁N₃O₂
Molecular Weight:265.271
Hs Code.:
European Community (EC) Number:808-704-7
ChEMBL ID:CHEMBL1739908
Mol file:33683-30-6.mol

Synonyms:4-(quinazolin-4-ylamino)benzoic acid;33683-30-6;4-[(quinazolin-4-yl)amino]benzoic acid;4-(quinazolin-4-ylamino)-benzoic acid;MFCD02322970;ChemDiv2_004018;Oprea1_059954;Oprea1_142855;SCHEMBL5527448;CHEMBL1739908;HMS1380G14;STK968949;AKOS000273014;4-[(quinazolin-4-yl)amino]benzoicacid;IDI1_002733;CS-0451220;EN300-10404;Z57000604

Suppliers and Price of 4-(Quinazolin-4-ylamino)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-(Quinazolin-4-ylamino)benzoic acid
1g
$ 201.00

AK Scientific
4-(Quinazolin-4-ylamino)benzoic acid
2.5g
$ 648.00

Total 3 raw suppliers

Chemical Property of 4-(Quinazolin-4-ylamino)benzoic acid

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:265.085126602
Heavy Atom Count:20
Complexity:342

Purity/Quality:

97% ^*data from raw suppliers

4-(Quinazolin-4-ylamino)benzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)C(=O)O

Technology Process of 4-(Quinazolin-4-ylamino)benzoic acid

There total 3 articles about 4-(Quinazolin-4-ylamino)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 619-45-4
4-methoxycarbonyl aniline

: 33683-30-6
4-(quinazolin-4-ylamino)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 0.5 h / 40 - 50 °C

2: sodium hydroxide / water; methanol / 2 h / Reflux

With sodium hydroxide; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1134/S106816202002017X

Reference yield:

: 5190-68-1
4-chloroquinazoline

: 33683-30-6
4-(quinazolin-4-ylamino)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 0.5 h / 40 - 50 °C

2: sodium hydroxide / water; methanol / 2 h / Reflux

With sodium hydroxide; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1134/S106816202002017X