DPEPhosPd(Br)Me

Base Information

• Chemical Name: DPEPhosPd(Br)Me
• CAS No.: 459868-21-4
• Molecular Formula: C₃₇H₃₁BrOP₂Pd
• Molecular Weight: 739.924
• Mol file: 459868-21-4.mol

Synonyms:

Chemical Property of DPEPhosPd(Br)Me

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of DPEPhosPd(Br)Me

There total 3 articles about DPEPhosPd(Br)Me which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(N,N,N',N'-tetramethylethylenediamine)dimethylpalladium(II) + 2-bromo-N,Ν-diethyl-2,2-difluoroacetamide (2643-22-3) + bis[2-(diphenylphosphino)phenyl] ether (166330-10-5) → DPEPhosPd(Br)Me (459868-21-4)

Guidance literature:

2-bromo-N,Ν-diethyl-2,2-difluoroacetamide; bis[2-(diphenylphosphino)phenyl] ether; In benzene; for 0.0166667h; Glovebox; Inert atmosphere;

(N,N,N',N'-tetramethylethylenediamine)dimethylpalladium(II); In benzene; at 70 ℃; for 20h; Glovebox; Inert atmosphere; Sealed tube; Darkness;

DOI:10.1021/acs.organomet.6b00893

Reference yield:

(N,N,N',N'-tetramethylethylenediamine)dimethylpalladium(II) + 2-bromo-N,Ν-diethyl-2,2-difluoroacetamide (2643-22-3) + bis[2-(diphenylphosphino)phenyl] ether (166330-10-5) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → DPEPhosPd(Br)Me (459868-21-4) + N,N-diethyl-2,2-difluoro-2-phenylacetamide

Guidance literature:

2-bromo-N,Ν-diethyl-2,2-difluoroacetamide; bis[2-(diphenylphosphino)phenyl] ether; benzene; With potassium carbonate; for 0.0166667h; Glovebox; Inert atmosphere;

(N,N,N',N'-tetramethylethylenediamine)dimethylpalladium(II); at 70 ℃; for 24h; Glovebox; Inert atmosphere; Sealed tube; Darkness;

DOI:10.1021/acs.organomet.6b00893

Reference yield:

[Pd(C8H12)(CH3)Br] (295338-48-6) + bis[2-(diphenylphosphino)phenyl] ether (166330-10-5) → DPEPhosPd(Br)Me (459868-21-4)

Guidance literature:

In benzene; ligand added to soln. of Pd complex (molar ratio 1.05:1) in benzene; stirred for 1 h; filtered; ppt. washed with benzene and Et2O; dried in vac.;

DOI:10.1039/b111596k

upstream raw materials:

[Pd(C₈H₁₂)(CH₃)Br]

bis[2-(diphenylphosphino)phenyl] ether

2-bromo-N,Ν-diethyl-2,2-difluoroacetamide

benzene