Technology Process of C28H38N4O4
There total 5 articles about C28H38N4O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C21H25NO6;
With
triethylsilane; N,N-diethyl-N-isopropylamine; C23H22NOPolS; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; trifluoroacetic acid;
In
1-methyl-pyrrolidin-2-one; dichloromethane;
at 20 ℃;
Inert atmosphere;
solid phase reaction;
With
triethylsilane; trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
solid phase reaction;
C15H21NO6; C12H14N2O4S2; C24H33NO6;
Further stages;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diisobutylaluminium hydride / dichloromethane / 2 h / -78 - 0 °C / Inert atmosphere
2.1: copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; triethylamine / acetonitrile / 20 °C / Inert atmosphere
3.1: platinum(IV) oxide; hydrogen / ethanol / 20 °C / Inert atmosphere
3.2: MP-TMT resin / 20 °C / Inert atmosphere
4.1: triethylsilane; C23H22NOPolS; N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; trifluoroacetic acid / 1-methyl-pyrrolidin-2-one; dichloromethane / 20 °C / Inert atmosphere; solid phase reaction
4.2: 20 °C / Inert atmosphere; solid phase reaction
With
triethylsilane; platinum(IV) oxide; copper(l) iodide; trans-bis(triphenylphosphine)palladium dichloride; N,N-diethyl-N-isopropylamine; C23H22NOPolS; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; diisobutylaluminium hydride; triethylamine; trifluoroacetic acid;
In
1-methyl-pyrrolidin-2-one; ethanol; dichloromethane; acetonitrile;
2.1: Sonogashira coupling;
DOI:10.1021/jm2007062
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: platinum(IV) oxide; hydrogen / ethanol / 20 °C / Inert atmosphere
1.2: MP-TMT resin / 20 °C / Inert atmosphere
2.1: triethylsilane; C23H22NOPolS; N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; trifluoroacetic acid / 1-methyl-pyrrolidin-2-one; dichloromethane / 20 °C / Inert atmosphere; solid phase reaction
2.2: 20 °C / Inert atmosphere; solid phase reaction
With
triethylsilane; platinum(IV) oxide; N,N-diethyl-N-isopropylamine; C23H22NOPolS; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; trifluoroacetic acid;
In
1-methyl-pyrrolidin-2-one; ethanol; dichloromethane;
DOI:10.1021/jm2007062