Benzene, 1-[(1,1-dimethylethyl)thio]-4-ethynyl-

Base Information

Chemical Name:Benzene, 1-[(1,1-dimethylethyl)thio]-4-ethynyl-
CAS No.:135883-45-3
Molecular Formula:C12H14S
Molecular Weight:190.309
Hs Code.:
Mol file:135883-45-3.mol

Synonyms:1-tert-Butylsulfanyl-4-ethynyl-benzene;4-ethynylphenyl tert-butyl sulfide;tert-butyl(4-ethynylphenyl)sulfane;1-tert-butylthio-4-ethynylbenzene;1-tert-butylsulfanyl-4-ethynylbenzene;

Suppliers and Price of Benzene, 1-[(1,1-dimethylethyl)thio]-4-ethynyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Benzene, 1-[(1,1-dimethylethyl)thio]-4-ethynyl-

Chemical Property:

PSA：25.30000
LogP:3.55850

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzene, 1-[(1,1-dimethylethyl)thio]-4-ethynyl-

There total 6 articles about Benzene, 1-[(1,1-dimethylethyl)thio]-4-ethynyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 135883-41-9
1-(tert-butylsulfanyl)-4-(trimethylsilylethynyl)benzene

: 135883-45-3
1-(tert-butylsulfanyl)-4-ethynylbenzene

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃;
DOI:10.1002/anie.200352179

Reference yield: 98.0%

: 795274-48-5
1-tert-butylsulfanyl-4-(2'-triisopropylsilylethynyl)-benzene

: 135883-45-3
1-(tert-butylsulfanyl)-4-ethynylbenzene

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1039/b408677e

Reference yield:

: 25752-90-3
tert-butyl 4-bromophenyl sulfide

: 135883-45-3
1-(tert-butylsulfanyl)-4-ethynylbenzene

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / diisopropylamine / dichlorobis(triphenylphosphine)palladium(II); copper(I) iodide / tetrahydrofuran / 40 h / Heating

2: 100 percent / n-Bu₄NF / tetrahydrofuran / 3 h

With tetrabutyl ammonium fluoride; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; In tetrahydrofuran; 1: Sonogashira cross-coupling;
DOI:10.1021/ol0606278