C₁₆H₁₉Cl₂N₃O

Base Information

Chemical Name:C₁₆H₁₉Cl₂N₃O
CAS No.:677742-30-2
Molecular Formula:C₁₆H₁₉Cl₂N₃O
Molecular Weight:340.252
Hs Code.:

C<sub>16</sub>H<sub>19</sub>Cl<sub>2</sub>N<sub>3</sub>O

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₁₆H₁₉Cl₂N₃O

Chemical Property:

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Technology Process of C₁₆H₁₉Cl₂N₃O

There total 6 articles about C₁₆H₁₉Cl₂N₃O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 677742-29-9
C₁₆H₁₇Cl₂N₃O₃

: 677742-30-2
C₁₆H₁₉Cl₂N₃O

Guidance literature:: With hydrogen; In ethanol; under 2585.81 Torr;
DOI:10.1016/j.bmcl.2012.06.034

Reference yield:

: 165547-79-5
2-hydroxy-3-nitro-4-chloropyridine

: 677742-30-2
C₁₆H₁₉Cl₂N₃O

Guidance literature:: Multi-step reaction with 6 steps

1: silver nitrate / benzene / 5 h

2: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / ethanol; toluene / 80 °C

3: trifluoroacetic acid / dichloromethane

4: trichlorophosphate / N,N-dimethyl-formamide / 95 °C

5: N-ethyl-N,N-diisopropylamine / butan-1-ol

6: ; hydrogen / ethanol / 2585.81 Torr

With bis-triphenylphosphine-palladium(II) chloride; hydrogen; sodium carbonate; silver nitrate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; trichlorophosphate; In ethanol; dichloromethane; N,N-dimethyl-formamide; toluene; butan-1-ol; benzene; 2: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.06.034

Reference yield:

: 219735-84-9
2-benzyloxy-4-chloro-3-nitropyridine

: 677742-30-2
C₁₆H₁₉Cl₂N₃O

Guidance literature:: Multi-step reaction with 5 steps

1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate / ethanol; toluene / 80 °C

2: trifluoroacetic acid / dichloromethane

3: trichlorophosphate / N,N-dimethyl-formamide / 95 °C

4: N-ethyl-N,N-diisopropylamine / butan-1-ol

5: ; hydrogen / ethanol / 2585.81 Torr

With bis-triphenylphosphine-palladium(II) chloride; hydrogen; sodium carbonate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; trichlorophosphate; In ethanol; dichloromethane; N,N-dimethyl-formamide; toluene; butan-1-ol; 1: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.06.034